ID   DNCH_TRIV2              Reviewed;         148 AA.
AC   Q3MG63;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=1,4-dihydroxy-2-naphthoyl-CoA hydrolase {ECO:0000255|HAMAP-Rule:MF_02101};
DE            Short=DHNA-CoA hydrolase {ECO:0000255|HAMAP-Rule:MF_02101};
DE            EC=3.1.2.28 {ECO:0000255|HAMAP-Rule:MF_02101};
DE   AltName: Full=DHNA-CoA thioesterase {ECO:0000255|HAMAP-Rule:MF_02101};
GN   OrderedLocusNames=Ava_0397;
OS   Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29413 / PCC 7937;
RX   PubMed=25197444; DOI=10.4056/sigs.3899418;
RA   Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA   Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT   "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL   Stand. Genomic Sci. 9:562-573(2014).
CC   -!- FUNCTION: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA
CC       (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in
CC       phylloquinone (vitamin K1) biosynthesis. {ECO:0000255|HAMAP-
CC       Rule:MF_02101}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-
CC         naphthoate + CoA + H(+); Xref=Rhea:RHEA:26309, ChEBI:CHEBI:11173,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:58897; EC=3.1.2.28; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_02101};
CC   -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_02101}.
CC   -!- PATHWAY: Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate
CC       biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 7/7.
CC       {ECO:0000255|HAMAP-Rule:MF_02101}.
CC   -!- SIMILARITY: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
CC       DHNA-CoA hydrolase subfamily. {ECO:0000255|HAMAP-Rule:MF_02101}.
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DR   EMBL; CP000117; ABA20023.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q3MG63; -.
DR   SMR; Q3MG63; -.
DR   STRING; 240292.Ava_0397; -.
DR   EnsemblBacteria; ABA20023; ABA20023; Ava_0397.
DR   KEGG; ava:Ava_0397; -.
DR   eggNOG; COG0824; Bacteria.
DR   HOGENOM; CLU_101141_5_3_3; -.
DR   OMA; IVNCEAN; -.
DR   UniPathway; UPA00995; -.
DR   UniPathway; UPA01057; UER01033.
DR   Proteomes; UP000002533; Chromosome.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02101; DHNA_CoA_hydrolase; 1.
DR   InterPro; IPR022829; DHNA_CoA_hydrolase.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR006683; Thioestr_dom.
DR   Pfam; PF03061; 4HBT; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..148
FT                   /note="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
FT                   /id="PRO_0000377009"
FT   ACT_SITE        15
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02101"
SQ   SEQUENCE   148 AA;  16942 MW;  B37545ACC617BA04 CRC64;
     MPFTYHRTIH FQDTDAAGVV YFANILSICH EGYEASLRTS GISLKEFFTN PNMAFPIVHA
     SVDFLRPLFC GDQVIISLVP QKIGAEKFEI NYEIYLADVL VAKAVTRHVC IDANTRSKQE
     LSTEIIQWLD GYRKETEEVE RRKAREVV