ID   DNF1_LOCMI              Reviewed;           9 AA.
AC   P16339;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   11-DEC-2019, entry version 66.
DE   RecName: Full=Locupressin;
DE   AltName: Full=Diuretic neuropeptide F1/F2;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT GLY-9.
RC   TISSUE=Subesophageal ganglion, and Thoracic ganglion;
RX   PubMed=3689410; DOI=10.1016/0006-291x(87)91621-4;
RA   Proux J.P., Miller C.A., Li J.P., Carney R.L., Girardie A., Delaage M.,
RA   Schooley D.A.;
RT   "Identification of an arginine vasopressin-like diuretic hormone from
RT   Locusta migratoria.";
RL   Biochem. Biophys. Res. Commun. 149:180-186(1987).
CC   -!- FUNCTION: Diuretic hormone.
CC   -!- SUBUNIT: Monomer (F1) and homodimer (F2); disulfide-linked.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR   PIR; A29477; A29477.
DR   PRIDE; P16339; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR022423; Neurohypophysial_hormone_CS.
DR   Pfam; PF00220; Hormone_4; 1.
DR   PROSITE; PS00264; NEUROHYPOPHYS_HORM; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Hormone;
KW   Neuropeptide; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Locupressin"
FT                   /id="PRO_0000044100"
FT   MOD_RES         9
FT                   /note="Glycine amide"
FT                   /evidence="ECO:0000269|PubMed:3689410"
FT   DISULFID        1..6
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        1..6
FT                   /note="In monomeric form"
FT   DISULFID        1
FT                   /note="Interchain (with C-6); in dimeric form"
FT   DISULFID        6
FT                   /note="Interchain (with C-1); in dimeric form"
SQ   SEQUENCE   9 AA;  976 MW;  56EB176EB451A057 CRC64;
     CLITNCPRG