DNJ10_CAEEL
ID DNJ10_CAEEL Reviewed; 456 AA.
AC Q8TA83; P34408; Q95QJ6;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=DnaJ homolog dnj-10;
DE AltName: Full=DnaJ domain protein 10;
GN Name=dnj-10; ORFNames=F22B7.5;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a {ECO:0000303|PubMed:9851916};
CC IsoId=Q8TA83-1; Sequence=Displayed;
CC Name=b {ECO:0000303|PubMed:9851916};
CC IsoId=Q8TA83-2; Sequence=VSP_051736;
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DR EMBL; FO080222; CCD62135.1; -; Genomic_DNA.
DR EMBL; FO080222; CCD62136.1; -; Genomic_DNA.
DR RefSeq; NP_498901.1; NM_066500.4. [Q8TA83-2]
DR RefSeq; NP_498902.1; NM_066501.3. [Q8TA83-1]
DR AlphaFoldDB; Q8TA83; -.
DR SMR; Q8TA83; -.
DR BioGRID; 41415; 21.
DR DIP; DIP-24664N; -.
DR IntAct; Q8TA83; 12.
DR STRING; 6239.F22B7.5a; -.
DR EPD; Q8TA83; -.
DR PaxDb; Q8TA83; -.
DR PeptideAtlas; Q8TA83; -.
DR EnsemblMetazoa; F22B7.5a.1; F22B7.5a.1; WBGene00001028. [Q8TA83-1]
DR EnsemblMetazoa; F22B7.5b.1; F22B7.5b.1; WBGene00001028. [Q8TA83-2]
DR GeneID; 176211; -.
DR KEGG; cel:CELE_F22B7.5; -.
DR UCSC; F22B7.5a.1; c. elegans. [Q8TA83-1]
DR CTD; 176211; -.
DR WormBase; F22B7.5a; CE24911; WBGene00001028; dnj-10. [Q8TA83-1]
DR WormBase; F22B7.5b; CE27991; WBGene00001028; dnj-10. [Q8TA83-2]
DR eggNOG; KOG0715; Eukaryota.
DR GeneTree; ENSGT00940000155280; -.
DR HOGENOM; CLU_017633_0_5_1; -.
DR InParanoid; Q8TA83; -.
DR OMA; DLHCTVT; -.
DR OrthoDB; 894595at2759; -.
DR PhylomeDB; Q8TA83; -.
DR SignaLink; Q8TA83; -.
DR PRO; PR:Q8TA83; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00001028; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005739; C:mitochondrion; ISS:WormBase.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0031072; F:heat shock protein binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051082; F:unfolded protein binding; ISS:WormBase.
DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
DR GO; GO:0007005; P:mitochondrion organization; IBA:GO_Central.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IBA:GO_Central.
DR GO; GO:0002119; P:nematode larval development; IMP:WormBase.
DR GO; GO:0006457; P:protein folding; ISS:WormBase.
DR GO; GO:0009408; P:response to heat; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd10719; DnaJ_zf; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR HAMAP; MF_01152; DnaJ; 1.
DR InterPro; IPR012724; DnaJ.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR001305; HSP_DnaJ_Cys-rich_dom.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR InterPro; IPR036869; J_dom_sf.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR Pfam; PF00684; DnaJ_CXXCXGXG; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR SUPFAM; SSF49493; SSF49493; 2.
DR SUPFAM; SSF57938; SSF57938; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS51188; ZF_CR; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Chaperone; Metal-binding; Reference proteome; Repeat;
KW Zinc; Zinc-finger.
FT CHAIN 1..456
FT /note="DnaJ homolog dnj-10"
FT /id="PRO_0000071136"
FT DOMAIN 44..108
FT /note="J"
FT /evidence="ECO:0000255"
FT REPEAT 208..215
FT /note="CXXCXGXG motif"
FT REPEAT 231..238
FT /note="CXXCXGXG motif"
FT REPEAT 245..252
FT /note="CXXCXGXG motif"
FT ZN_FING 178..257
FT /note="CR-type"
FT REGION 395..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..433
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 418..456
FT /note="GASESQKRRSEPVAENAETIDENQENEGFFEKIKRKIFG -> DKSEEKSES
FT KEEPKNEESSETPEKKAAES (in isoform b)"
FT /evidence="ECO:0000303|PubMed:9851916"
FT /id="VSP_051736"
SQ SEQUENCE 456 AA; 50136 MW; 94168108B65B73B4 CRC64;
MFVLNRSSGL IHRSVPLLAQ VSTPTTSTTK LAQLHTTHAL SKEDYYKTLG VDKKSDAKAI
KKAYFQLAKK YHPDVNKTKE AQTKFQEISE AYEVLSDDTK RQEYDAYGSG GGPAGGRGGA
GGFHHHGNVD VNEIFRRAFG GGGGMGGFNF DNFAQSAFGH SAAQEMVMDI SFEEAVRGAT
KNVSVNVVED CLKCHGTQVE PGHKKTSCPY CNGTGAVSQR LQGGFFYQTT CNRCRGSGHY
NKNPCQECEG EGQTVQRRQV SFNVPAGTNN GDSLKFQVGK NQLFVRFNVA PSLKFRREKD
DIHCDVDISL AQAVLGGTVK VPGINGDTYV HIPAGTGSHT KMRLTGKGVK RLHSYGNGDQ
YMHIKVTVPK YLTAEQKQIM LAWAATEQLK DGTIKGLEKN QKTEEKETKK NEEKKSEGAS
ESQKRRSEPV AENAETIDEN QENEGFFEKI KRKIFG
