DNJ20_CAEEL
ID DNJ20_CAEEL Reviewed; 355 AA.
AC Q8MPX3; B3GWA8; Q10005;
DT 09-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=DnaJ homolog dnj-20;
DE AltName: Full=DnaJ domain protein 20;
DE Flags: Precursor;
GN Name=dnj-20 {ECO:0000312|WormBase:T15H9.7a};
GN ORFNames=T15H9.7 {ECO:0000312|WormBase:T15H9.7a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a {ECO:0000312|WormBase:T15H9.7a};
CC IsoId=Q8MPX3-1; Sequence=Displayed;
CC Name=b {ECO:0000312|WormBase:T15H9.7b};
CC IsoId=Q8MPX3-2; Sequence=VSP_036008;
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z47356; CAA87414.2; -; Genomic_DNA.
DR EMBL; Z47356; CAQ58123.1; -; Genomic_DNA.
DR PIR; T24938; T24938.
DR RefSeq; NP_496072.2; NM_063671.5. [Q8MPX3-2]
DR RefSeq; NP_741036.2; NM_171030.4.
DR AlphaFoldDB; Q8MPX3; -.
DR SMR; Q8MPX3; -.
DR BioGRID; 39837; 3.
DR IntAct; Q8MPX3; 1.
DR STRING; 6239.T15H9.7a; -.
DR EPD; Q8MPX3; -.
DR PaxDb; Q8MPX3; -.
DR PeptideAtlas; Q8MPX3; -.
DR EnsemblMetazoa; T15H9.7a.1; T15H9.7a.1; WBGene00001038. [Q8MPX3-1]
DR EnsemblMetazoa; T15H9.7b.1; T15H9.7b.1; WBGene00001038. [Q8MPX3-2]
DR GeneID; 174514; -.
DR UCSC; T15H9.7; c. elegans. [Q8MPX3-1]
DR CTD; 174514; -.
DR WormBase; T15H9.7a; CE01664; WBGene00001038; dnj-20. [Q8MPX3-1]
DR WormBase; T15H9.7b; CE30689; WBGene00001038; dnj-20. [Q8MPX3-2]
DR eggNOG; KOG0713; Eukaryota.
DR GeneTree; ENSGT00940000155792; -.
DR HOGENOM; CLU_017633_0_0_1; -.
DR InParanoid; Q8MPX3; -.
DR OMA; WDAGFEF; -.
DR OrthoDB; 687505at2759; -.
DR PhylomeDB; Q8MPX3; -.
DR PRO; PR:Q8MPX3; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00001038; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0051787; F:misfolded protein binding; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR GO; GO:0051604; P:protein maturation; IBA:GO_Central.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR036869; J_dom_sf.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR SUPFAM; SSF49493; SSF49493; 2.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Chaperone; Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..355
FT /note="DnaJ homolog dnj-20"
FT /id="PRO_0000007270"
FT DOMAIN 24..89
FT /note="J"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT VAR_SEQ 1..273
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_036008"
SQ SEQUENCE 355 AA; 39861 MW; 95FA4D8E551D9CC2 CRC64;
MRILNVSLLV LASSLVAFVE CGRDFYKILG VAKNANANQI KKAYRKLAKE LHPDRNQDDE
MANEKFQDLS SAYEVLSDKE KRAMYDRHGE EGVAKMGGGG GGGHDPFSSF FGDFFGGGGG
HGGEEGTPKG ADVTIDLFVT LEEVYNGHFV EIKRKKAVYK QTSGTRQCNC RHEMRTEQMG
QGRFQMFQVK VCDECPNVKL VQENKVLEVE VEVGADNGHQ QIFHGEGEPH IEGDPGDLKF
KIRIQKHPRF ERKGDDLYTN VTISLQDALN GFEMEIQHLD GHIVKVQRDK VTWPGARLRK
KDEGMPSLED NNKKGMLVVT FDVEFPKTEL SDEQKAQIIE ILQQNTVKPK AYNGL