DNJ49_ARATH
ID DNJ49_ARATH Reviewed; 354 AA.
AC Q9FH28; Q67XE5;
DT 25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 2.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Chaperone protein dnaJ 49;
DE Short=AtDjC49;
DE Short=AtJ49;
GN Name=ATJ49; Synonyms=C49; OrderedLocusNames=At5g49060;
GN ORFNames=K19E20.16, K20J1_3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 183-354.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11599562; DOI=10.1379/1466-1268(2001)006<0209:tjdpoa>2.0.co;2;
RA Miernyk J.A.;
RT "The J-domain proteins of Arabidopsis thaliana: an unexpectedly large and
RT diverse family of chaperones.";
RL Cell Stress Chaperones 6:209-218(2001).
CC -!- FUNCTION: Plays a continuous role in plant development probably in the
CC structural organization of compartments. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the DnaJ family. C/III subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10088.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB023028; BAB10088.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95767.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69562.1; -; Genomic_DNA.
DR EMBL; AK176874; BAD44637.1; -; mRNA.
DR RefSeq; NP_001331231.1; NM_001344813.1.
DR RefSeq; NP_199717.2; NM_124283.5.
DR AlphaFoldDB; Q9FH28; -.
DR SMR; Q9FH28; -.
DR BioGRID; 20211; 1.
DR IntAct; Q9FH28; 1.
DR STRING; 3702.AT5G49060.1; -.
DR PaxDb; Q9FH28; -.
DR PRIDE; Q9FH28; -.
DR ProteomicsDB; 222088; -.
DR EnsemblPlants; AT5G49060.1; AT5G49060.1; AT5G49060.
DR EnsemblPlants; AT5G49060.2; AT5G49060.2; AT5G49060.
DR GeneID; 834965; -.
DR Gramene; AT5G49060.1; AT5G49060.1; AT5G49060.
DR Gramene; AT5G49060.2; AT5G49060.2; AT5G49060.
DR KEGG; ath:AT5G49060; -.
DR Araport; AT5G49060; -.
DR TAIR; locus:2155184; AT5G49060.
DR eggNOG; KOG0714; Eukaryota.
DR HOGENOM; CLU_043579_4_0_1; -.
DR InParanoid; Q9FH28; -.
DR OMA; AYCRKPA; -.
DR OrthoDB; 1173544at2759; -.
DR PhylomeDB; Q9FH28; -.
DR PRO; PR:Q9FH28; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FH28; baseline and differential.
DR Genevisible; Q9FH28; AT.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0030544; F:Hsp70 protein binding; IBA:GO_Central.
DR GO; GO:0071218; P:cellular response to misfolded protein; IBA:GO_Central.
DR GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IBA:GO_Central.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR015399; DUF1977_DnaJ-like.
DR InterPro; IPR036869; J_dom_sf.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF09320; DUF1977; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 2: Evidence at transcript level;
KW Chaperone; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..354
FT /note="Chaperone protein dnaJ 49"
FT /id="PRO_0000071086"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 99..163
FT /note="J"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
SQ SEQUENCE 354 AA; 41223 MW; 454264542B43C2EA CRC64;
MDGNKDDASR CLRIAEDAIV SGDKERALKF INMAKRLNPS LSVDELVAAC DNLDSVSRNS
SVSEKLKTMD GDDDKLETGK MKYTEENVDL VRNIIRNNDY YAILGLEKNC SVDEIRKAYR
KLSLKVHPDK NKAPGSEEAF KKVSKAFTCL SDGNSRRQFD QVGIVDEFDH VQRRNRRPRR
RYNTRNDFFD DEFDPEEIFR TVFGQQREVF RASHAYRTRQ PRNQFREEEI NVAGPSCLTI
IQILPFFLLL LLAYLPFSEP DYSLHKNQSY QIPKTTQNTE ISFYVRSASA FDEKFPLSSS
ARANLEGNVI KEYKHFLFQS CRIELQKRRW NKKIPTPHCI ELQDRGFVDR HIPI
