DNJ5_CAEEL
ID DNJ5_CAEEL Reviewed; 915 AA.
AC Q09446; Q95QY2; Q95QY3; Q95QY4;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 06-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=DnaJ homolog dnj-5;
DE AltName: Full=DnaJ domain protein 5;
GN Name=dnj-5; ORFNames=C04A2.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Comment=Experimental confirmation may be lacking for some isoforms.;
CC Name=A;
CC IsoId=Q09446-1; Sequence=Displayed;
CC Name=B;
CC IsoId=Q09446-2; Sequence=VSP_001299, VSP_001301;
CC Name=C;
CC IsoId=Q09446-3; Sequence=VSP_001298, VSP_001300;
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DR EMBL; FO080320; CCD62846.1; -; Genomic_DNA.
DR EMBL; FO080320; CCD62847.1; -; Genomic_DNA.
DR EMBL; FO080320; CCD62848.1; -; Genomic_DNA.
DR RefSeq; NP_495400.2; NM_062999.6. [Q09446-1]
DR RefSeq; NP_495401.2; NM_063000.6.
DR RefSeq; NP_741015.1; NM_171014.4. [Q09446-3]
DR AlphaFoldDB; Q09446; -.
DR SMR; Q09446; -.
DR STRING; 6239.C04A2.7a.1; -.
DR EPD; Q09446; -.
DR PaxDb; Q09446; -.
DR PeptideAtlas; Q09446; -.
DR EnsemblMetazoa; C04A2.7a.1; C04A2.7a.1; WBGene00001023. [Q09446-1]
DR EnsemblMetazoa; C04A2.7b.1; C04A2.7b.1; WBGene00001023. [Q09446-2]
DR EnsemblMetazoa; C04A2.7c.1; C04A2.7c.1; WBGene00001023. [Q09446-3]
DR GeneID; 174122; -.
DR KEGG; cel:CELE_C04A2.7; -.
DR UCSC; C04A2.7a; c. elegans. [Q09446-1]
DR CTD; 174122; -.
DR WormBase; C04A2.7a; CE29657; WBGene00001023; dnj-5. [Q09446-1]
DR WormBase; C04A2.7b; CE29658; WBGene00001023; dnj-5. [Q09446-2]
DR WormBase; C04A2.7c; CE29659; WBGene00001023; dnj-5. [Q09446-3]
DR eggNOG; KOG0720; Eukaryota.
DR HOGENOM; CLU_340739_0_0_1; -.
DR InParanoid; Q09446; -.
DR OMA; CEPREED; -.
DR OrthoDB; 580949at2759; -.
DR PRO; PR:Q09446; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00001023; Expressed in adult organism and 4 other tissues.
DR ExpressionAtlas; Q09446; baseline and differential.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR032843; Jiv.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF14901; Jiv90; 1.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Alternative splicing; Chaperone; Reference proteome.
FT CHAIN 1..915
FT /note="DnaJ homolog dnj-5"
FT /id="PRO_0000071135"
FT DOMAIN 660..724
FT /note="J"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 160
FT /note="Missing (in isoform C)"
FT /evidence="ECO:0000305"
FT /id="VSP_001298"
FT VAR_SEQ 821..849
FT /note="SQRAMLKNMRAHTHNVQYRLLSPMFKNSD -> KNKKAELISNDGCRWTKEH
FT QINKRRYPTK (in isoform B)"
FT /evidence="ECO:0000305"
FT /id="VSP_001299"
FT VAR_SEQ 845..846
FT /note="Missing (in isoform C)"
FT /evidence="ECO:0000305"
FT /id="VSP_001300"
FT VAR_SEQ 850..915
FT /note="Missing (in isoform B)"
FT /evidence="ECO:0000305"
FT /id="VSP_001301"
SQ SEQUENCE 915 AA; 102740 MW; 1B38BD98DC4133C1 CRC64;
MSSFDDPEKH FLGNLLEDDP GSSVTSATSP FAGINGSTST ALTSQVPTVG PVMCPTELSM
SNAWPEPPPP YSPRHESWGL PSNANTTLLG SSSLTSSNWF PFTDQKETSS NEILSSLNLA
AGSSSPALPS TPSRVPHHPS SQVHHFHHNL HHHTHTHNVQ VQNHYFGAPP PGLESFGPTR
TSSTSSSQIY DAIPNPSWNY TGLSNINADS NVLFSDWKNK NSSQTSPVST VVSESSISSN
LETRPVHPPL SPSEVVEIAK EKKNVSKSYA EHLSKSTAGT QKKGAPIGAE KKQKQELAKK
MSNQLPIESI ATRIVVKGQP HSAPVVSRMP FSYRDVAARS DHTSSSNHPN HQPDELQRKE
LSSADLKLND SKAVRTKNND HRETGKTRNT IDPTDFNKKN RVDNEFQKIN NRKNKKEKAV
TEVAAPVIFE GVHPVDSSSR YDVLKNLESP NQSYHEKKSA NGRPPLIQKI FSRSSSPADD
IIDTEEEDPH RVRSSSTHVH QNGNGQVKKD QRKRVAQVNQ RRRKGRKEEP SWLQNAFSTF
VDVLFFVWGY ACFGLQWTLL LIVEVCQKIA DIFVTFGKSL WAGTCKGLRN VILAFVYLCF
FVVFAIKSVV VRLLTFINMI GAEESDETVE EQDWGCKKEI PIATNATEFA DRLSRETIRD
AYSVFGLRSD CSDDDIKRNY KRLAALVSPD KCTIDAADQV YELVDVAFSA IGYKDSRSEY
TLENLKNNEV HEQLISVWND MTKAVEEARN TIFCDCENTH FRVATSISPS QARSCKRCGV
KHPAKQNDIW VEKRHLGLTS TYYTCTDNVV YDITSWATCK SQRAMLKNMR AHTHNVQYRL
LSPMFKNSDF DAQSQYYNSS YPSSSTDARF LSDLQEEYST LLRQRSLAQI SFKNCEPREE
DRSRRAANRR QKRWR