DNJB7_MOUSE
ID DNJB7_MOUSE Reviewed; 312 AA.
AC Q9QYI8; Q9DA41;
DT 18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=DnaJ homolog subfamily B member 7;
DE AltName: Full=mDj5;
GN Name=Dnajb7;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=CD-1;
RX PubMed=11147971; DOI=10.1379/1466-1268(2000)005<0098:mhdhco>2.0.co;2;
RA Ohtsuka K., Hata M.;
RT "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for
RT their classification and nomenclature.";
RL Cell Stress Chaperones 5:98-112(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- FUNCTION: Probably acts as a co-chaperone. {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA88303.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB028855; BAA88303.1; ALT_FRAME; mRNA.
DR EMBL; AK006201; BAB24456.1; -; mRNA.
DR EMBL; AK077186; BAC36668.1; -; mRNA.
DR CCDS; CCDS37148.1; -.
DR RefSeq; NP_067292.2; NM_021317.2.
DR AlphaFoldDB; Q9QYI8; -.
DR SMR; Q9QYI8; -.
DR STRING; 10090.ENSMUSP00000100712; -.
DR iPTMnet; Q9QYI8; -.
DR PhosphoSitePlus; Q9QYI8; -.
DR MaxQB; Q9QYI8; -.
DR PaxDb; Q9QYI8; -.
DR PRIDE; Q9QYI8; -.
DR ProteomicsDB; 279457; -.
DR Antibodypedia; 256; 41 antibodies from 17 providers.
DR DNASU; 57755; -.
DR Ensembl; ENSMUST00000057236; ENSMUSP00000100712; ENSMUSG00000047108.
DR GeneID; 57755; -.
DR KEGG; mmu:57755; -.
DR UCSC; uc007wwp.1; mouse.
DR CTD; 150353; -.
DR MGI; MGI:1914012; Dnajb7.
DR VEuPathDB; HostDB:ENSMUSG00000047108; -.
DR eggNOG; KOG0714; Eukaryota.
DR GeneTree; ENSGT00940000163470; -.
DR HOGENOM; CLU_017633_12_0_1; -.
DR InParanoid; Q9QYI8; -.
DR OMA; QYTFVDN; -.
DR OrthoDB; 1472647at2759; -.
DR PhylomeDB; Q9QYI8; -.
DR TreeFam; TF105142; -.
DR BioGRID-ORCS; 57755; 3 hits in 72 CRISPR screens.
DR PRO; PR:Q9QYI8; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q9QYI8; protein.
DR Bgee; ENSMUSG00000047108; Expressed in seminiferous tubule of testis and 30 other tissues.
DR Genevisible; Q9QYI8; MM.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0051087; F:chaperone binding; ISO:MGI.
DR GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0061077; P:chaperone-mediated protein folding; IBA:GO_Central.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.287.110; -; 1.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR036869; J_dom_sf.
DR Pfam; PF00226; DnaJ; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; SSF46565; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 2: Evidence at transcript level;
KW Chaperone; Reference proteome.
FT CHAIN 1..312
FT /note="DnaJ homolog subfamily B member 7"
FT /id="PRO_0000071028"
FT DOMAIN 3..69
FT /note="J"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00286"
FT REGION 272..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..312
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 126
FT /note="S -> T (in Ref. 1; BAA88303)"
FT /evidence="ECO:0000305"
FT CONFLICT 134
FT /note="G -> R (in Ref. 1; BAA88303)"
FT /evidence="ECO:0000305"
FT CONFLICT 137
FT /note="S -> P (in Ref. 1; BAA88303)"
FT /evidence="ECO:0000305"
FT CONFLICT 229
FT /note="A -> P (in Ref. 1; BAA88303)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 312 AA; 35626 MW; 20BBC3008316587A CRC64;
MVDYYEVLGV QRYASPEDIK RAYRKVALKW HPDKNPENKE EAERKFKEVA EAYEVLSNVE
KRDIYDKYGK EGLDGRGASH LDDEREYRFT FRKADDVFKE IFGERDPFSF HLFEDSLEGL
LNSSRSPSGS RGRGAGSHVS RAYDHPALSG LSSYDTGYSS YVSLGHEGLT SFSSLALDDS
GMGNYIPITP SGKVINGRNI NTKKAFENRQ EREAEDDSEL ISFLVNSVAN EEHFTDKCNW
RRQSFNNYSP NSYSSSNTTQ YTLVDNNEQG TSWVTNKKEP SIFSAGFKEG GRRKKKKHKE
GQKKKKSNKR NH
