ID   DNS2_BURP1              Reviewed;         350 AA.
AC   Q3JJK4;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative deoxyribonuclease-2;
DE            EC=3.1.-.-;
DE   AltName: Full=Deoxyribonuclease II;
GN   OrderedLocusNames=BURPS1710b_A1091;
OS   Burkholderia pseudomallei (strain 1710b).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=320372;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1710b;
RX   PubMed=20333227; DOI=10.1093/gbe/evq003;
RA   Losada L., Ronning C.M., DeShazer D., Woods D., Fedorova N., Kim H.S.,
RA   Shabalina S.A., Pearson T.R., Brinkac L., Tan P., Nandi T., Crabtree J.,
RA   Badger J., Beckstrom-Sternberg S., Saqib M., Schutzer S.E., Keim P.,
RA   Nierman W.C.;
RT   "Continuing evolution of Burkholderia mallei through genome reduction and
RT   large-scale rearrangements.";
RL   Genome Biol. Evol. 2:102-116(2010).
CC   -!- MISCELLANEOUS: Unlike their eukaryotic orthologs the putative
CC       Burkholderia deoxyribonuclease-2 are probably not secreted from the
CC       cell, as they do not have a signal sequence.
CC   -!- SIMILARITY: Belongs to the DNase II family. {ECO:0000305}.
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DR   EMBL; CP000125; ABA51955.1; -; Genomic_DNA.
DR   RefSeq; WP_004524950.1; NC_007435.1.
DR   AlphaFoldDB; Q3JJK4; -.
DR   SMR; Q3JJK4; -.
DR   EnsemblBacteria; ABA51955; ABA51955; BURPS1710b_A1091.
DR   GeneID; 56531902; -.
DR   KEGG; bpm:BURPS1710b_A1091; -.
DR   HOGENOM; CLU_053867_0_0_4; -.
DR   OMA; ILYNDQK; -.
DR   OrthoDB; 449055at2; -.
DR   Proteomes; UP000002700; Chromosome II.
DR   GO; GO:0004531; F:deoxyribonuclease II activity; IEA:InterPro.
DR   InterPro; IPR004947; DNase_II.
DR   PANTHER; PTHR10858; PTHR10858; 1.
DR   Pfam; PF03265; DNase_II; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..350
FT                   /note="Putative deoxyribonuclease-2"
FT                   /id="PRO_0000230668"
SQ   SEQUENCE   350 AA;  38837 MW;  4B5B6D59757B1B53 CRC64;
     MTISPRDEQN RSVDLWFAYK VPKLTKDTDS DSATGYEYVY YDREIGSVQK SPNRMNNPKG
     ALFYTLDSIF GDPGSTTGWI LYNDEMPADA DRSNNATLGH TKGVIAFDIA SNSALWLLHS
     WPKYTSPSAP GVPTPLYGQT FLCVSLDLET AGKIAAQMAL HQQPQVYLPR TAGLDHASPL
     YTLTQPLNAS APGDSDSLDF KTRGGAPFKV IAKNRKWGKD FWNDLVGPTL KADMDVETWI
     RGKIPPILDS DGVHKTYDIK FIDLRKLGAP WAWPETQDHA KWGITTTDDW VCVGDINRMV
     TQEKRGGGTI AFQDPQLWKA LSQTDLIVPP PGKTEAQARA MIHRTHQPAD