DOF18_ARATH
ID DOF18_ARATH Reviewed; 352 AA.
AC Q84JQ8; Q8LFE3; Q9SGV3;
DT 09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Dof zinc finger protein DOF1.8;
DE Short=AtDOF1.8;
GN Name=DOF1.8; OrderedLocusNames=At1g64620; ORFNames=F1N19.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12475498; DOI=10.1016/s1360-1385(02)02362-2;
RA Yanagisawa S.;
RT "The Dof family of plant transcription factors.";
RL Trends Plant Sci. 7:555-560(2002).
CC -!- FUNCTION: Transcription factor that binds specifically to a 5'-AA[AG]G-
CC 3' consensus core sequence. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF19678.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009519; AAF19678.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE34262.1; -; Genomic_DNA.
DR EMBL; BT004047; AAO42079.1; -; mRNA.
DR EMBL; BT005148; AAO50681.1; -; mRNA.
DR EMBL; AY084898; AAM61461.1; -; mRNA.
DR PIR; E96669; E96669.
DR RefSeq; NP_564836.1; NM_105137.3.
DR AlphaFoldDB; Q84JQ8; -.
DR BioGRID; 27991; 7.
DR IntAct; Q84JQ8; 1.
DR STRING; 3702.AT1G64620.1; -.
DR iPTMnet; Q84JQ8; -.
DR PaxDb; Q84JQ8; -.
DR PRIDE; Q84JQ8; -.
DR ProteomicsDB; 222106; -.
DR EnsemblPlants; AT1G64620.1; AT1G64620.1; AT1G64620.
DR GeneID; 842770; -.
DR Gramene; AT1G64620.1; AT1G64620.1; AT1G64620.
DR KEGG; ath:AT1G64620; -.
DR Araport; AT1G64620; -.
DR TAIR; locus:2019499; AT1G64620.
DR eggNOG; ENOG502QPN9; Eukaryota.
DR HOGENOM; CLU_036438_5_1_1; -.
DR InParanoid; Q84JQ8; -.
DR OMA; YPNVHDS; -.
DR OrthoDB; 1101510at2759; -.
DR PhylomeDB; Q84JQ8; -.
DR PRO; PR:Q84JQ8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q84JQ8; baseline and differential.
DR Genevisible; Q84JQ8; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR045174; Dof.
DR InterPro; IPR003851; Znf_Dof.
DR PANTHER; PTHR31992; PTHR31992; 1.
DR Pfam; PF02701; zf-Dof; 1.
DR PROSITE; PS01361; ZF_DOF_1; 1.
DR PROSITE; PS50884; ZF_DOF_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..352
FT /note="Dof zinc finger protein DOF1.8"
FT /id="PRO_0000074270"
FT ZN_FING 49..103
FT /note="Dof-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT REGION 24..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 51
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 54
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 76
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 79
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT CONFLICT 180
FT /note="N -> H (in Ref. 4; AAM61461)"
FT /evidence="ECO:0000305"
FT CONFLICT 208
FT /note="S -> A (in Ref. 4; AAM61461)"
FT /evidence="ECO:0000305"
FT CONFLICT 311
FT /note="N -> I (in Ref. 4; AAM61461)"
FT /evidence="ECO:0000305"
FT CONFLICT 315
FT /note="H -> R (in Ref. 4; AAM61461)"
FT /evidence="ECO:0000305"
FT CONFLICT 349
FT /note="G -> GG (in Ref. 4; AAM61461)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 352 AA; 37878 MW; 7B57F885F1EA3976 CRC64;
MDTAKWPQEF VVKPMNEIVT NTCLKQQSNP PSPATPVERK ARPEKDQALN CPRCNSLNTK
FCYYNNYSLT QPRYFCKDCR RYWTAGGSLR NIPVGGGVRK NKRSSSNSSS SSPSSSSSSK
KPLFANNNTP TPPLPHLNPK IGEAAATKVQ DLTFSQGFGN AHEVKDLNLA FSQGFGIGHN
HHSSIPEFLQ VVPSSSMKNN PLVSTSSSLE LLGISSSSAS SNSRPAFMSY PNVHDSSVYT
ASGFGLSYPQ FQEFMRPALG FSLDGGDPLR QEEGSSGTNN GRPLLPFESL LKLPVSSSST
NSGGNGNLKE NNDEHSDHEH EKEEGEADQS VGFWSGMLSA GASAAASGGS WQ
