DOF47_ARATH
ID DOF47_ARATH Reviewed; 246 AA.
AC Q84K52; Q9SZK0;
DT 09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Dof zinc finger protein DOF4.7 {ECO:0000305};
DE Short=AtDOF4.7 {ECO:0000303|PubMed:12475498};
DE AltName: Full=Protein DNA BINDING WITH ONE FINGER 4.7 {ECO:0000303|PubMed:12475498};
GN Name=DOF4.7 {ECO:0000303|PubMed:12475498}; OrderedLocusNames=At4g38000;
GN ORFNames=F20D10.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12475498; DOI=10.1016/s1360-1385(02)02362-2;
RA Yanagisawa S.;
RT "The Dof family of plant transcription factors.";
RL Trends Plant Sci. 7:555-560(2002).
RN [5]
RP FUNCTION, INTERACTION WITH ZFP2, SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RX PubMed=20466844; DOI=10.1104/pp.110.153247;
RA Wei P.C., Tan F., Gao X.Q., Zhang X.Q., Wang G.Q., Xu H., Li L.J., Chen J.,
RA Wang X.C.;
RT "Overexpression of AtDOF4.7, an Arabidopsis DOF family transcription
RT factor, induces floral organ abscission deficiency in Arabidopsis.";
RL Plant Physiol. 153:1031-1045(2010).
CC -!- FUNCTION: Transcription factor that binds specifically to a 5'-AA[AG]G-
CC 3' consensus core sequence. Involved in the negative regulation of
CC floral organ abscission by binding to the typical DOF 5'-AAAG-3'
CC sequences in the promoter of ADPG2/PGAZAT, and by down-regulating its
CC expression. ADPG2/PGAZAT is an abscission-related and cell wall
CC hydrolyzing polygalacturonase. May act through the interaction with
CC ZFP2, an abscission-related transcription factor.
CC {ECO:0000269|PubMed:20466844}.
CC -!- SUBUNIT: Interacts with ZFP2. {ECO:0000269|PubMed:20466844}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20466844}.
CC -!- TISSUE SPECIFICITY: Highly expressed at the base of all organs of the
CC flower, especially in the abscission zone (AZ) of petals, stamens and
CC sepals. Expressed at low levels in sepals, filaments, stigmatic
CC papillae, tips of young siliques, and at the base of pedicels and leaf
CC trichomes. {ECO:0000269|PubMed:20466844}.
CC -!- MISCELLANEOUS: Plants over-expressing DOF4.7 fail in the abscission of
CC floral organs (sepals, petals and stamens) after anthesis.
CC {ECO:0000269|PubMed:20466844}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB37540.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAB80465.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL035538; CAB37540.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL161592; CAB80465.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002687; AEE86862.1; -; Genomic_DNA.
DR EMBL; BT005767; AAO64171.1; -; mRNA.
DR EMBL; BT006092; AAP04077.1; -; mRNA.
DR PIR; T05627; T05627.
DR RefSeq; NP_195513.2; NM_119961.4.
DR AlphaFoldDB; Q84K52; -.
DR STRING; 3702.AT4G38000.1; -.
DR PaxDb; Q84K52; -.
DR PRIDE; Q84K52; -.
DR ProteomicsDB; 222123; -.
DR EnsemblPlants; AT4G38000.1; AT4G38000.1; AT4G38000.
DR GeneID; 829956; -.
DR Gramene; AT4G38000.1; AT4G38000.1; AT4G38000.
DR KEGG; ath:AT4G38000; -.
DR Araport; AT4G38000; -.
DR TAIR; locus:2121041; AT4G38000.
DR eggNOG; ENOG502R06Q; Eukaryota.
DR HOGENOM; CLU_1148595_0_0_1; -.
DR InParanoid; Q84K52; -.
DR OMA; MFQNVEL; -.
DR OrthoDB; 1262349at2759; -.
DR PhylomeDB; Q84K52; -.
DR PRO; PR:Q84K52; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q84K52; baseline and differential.
DR Genevisible; Q84K52; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010227; P:floral organ abscission; IMP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR045174; Dof.
DR InterPro; IPR003851; Znf_Dof.
DR PANTHER; PTHR31992; PTHR31992; 1.
DR Pfam; PF02701; zf-Dof; 1.
DR PROSITE; PS01361; ZF_DOF_1; 1.
DR PROSITE; PS50884; ZF_DOF_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..246
FT /note="Dof zinc finger protein DOF4.7"
FT /id="PRO_0000074290"
FT ZN_FING 41..95
FT /note="Dof-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 43
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 46
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 68
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
FT BINDING 71
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00071"
SQ SEQUENCE 246 AA; 27394 MW; 1C132DE9FBA3BD8C CRC64;
MMTSSHQSNT TGFKPRRIKT TAKPPRQINN KEPSPATQPV LKCPRCDSVN TKFCYYNNYS
LSQPRHYCKN CRRYWTRGGA LRNVPIGGST RNKNKPCSLQ VISSPPLFSN GTSSASRELV
RNHPSTAMMM MSSGGFSGYM FPLDPNFNLA SSSIESLSSF NQDLHQKLQQ QRLVTSMFLQ
DSLPVNEKTV MFQNVELIPP STVTTDWVFD RFATGGGATS GNHEDNDDGE GNLGNWFHNA
NNNALL
