ID   DOP1_SCHPO              Reviewed;        1687 AA.
AC   Q9C0Z4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Protein dopey;
GN   ORFNames=SPAPB21F2.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1671, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- FUNCTION: Involved in cellular morphogenesis. Required for traffic
CC       between late Golgi and early endosomes, and for the normal structure
CC       and organization of the endoplasmic reticulum (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Peripheral membrane
CC       protein. Note=Late Golgi. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dopey family. {ECO:0000305}.
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DR   EMBL; CU329670; CAC36891.1; -; Genomic_DNA.
DR   RefSeq; NP_592953.1; NM_001018353.2.
DR   AlphaFoldDB; Q9C0Z4; -.
DR   BioGRID; 279648; 33.
DR   STRING; 4896.SPAPB21F2.02.1; -.
DR   iPTMnet; Q9C0Z4; -.
DR   MaxQB; Q9C0Z4; -.
DR   PaxDb; Q9C0Z4; -.
DR   PRIDE; Q9C0Z4; -.
DR   EnsemblFungi; SPAPB21F2.02.1; SPAPB21F2.02.1:pep; SPAPB21F2.02.
DR   GeneID; 2543220; -.
DR   KEGG; spo:SPAPB21F2.02; -.
DR   PomBase; SPAPB21F2.02; -.
DR   VEuPathDB; FungiDB:SPAPB21F2.02; -.
DR   eggNOG; KOG3613; Eukaryota.
DR   HOGENOM; CLU_001197_0_0_1; -.
DR   InParanoid; Q9C0Z4; -.
DR   OMA; WIFITDT; -.
DR   PhylomeDB; Q9C0Z4; -.
DR   PRO; PR:Q9C0Z4; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; ISO:PomBase.
DR   GO; GO:0006895; P:Golgi to endosome transport; ISO:PomBase.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR040314; DOP1.
DR   InterPro; IPR007249; Dopey_N.
DR   PANTHER; PTHR14042; PTHR14042; 1.
DR   Pfam; PF04118; Dopey_N; 1.
PE   1: Evidence at protein level;
KW   Golgi apparatus; Membrane; Phosphoprotein; Protein transport;
KW   Reference proteome; Transport.
FT   CHAIN           1..1687
FT                   /note="Protein dopey"
FT                   /id="PRO_0000316224"
FT   MOD_RES         1671
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   1687 AA;  192654 MW;  AD4B87939A2940AC CRC64;
     MNTIIDASND AKYRKYQDAI RKCIALFQTV EQWPDYISFL TKLHKVLQTH SSFVNIPCSL
     LVSRALAECL SPGLPSGVHK KTLEVYDYIF TIIGSKTLTN ELSTWSYGLT PFFSISSIKT
     KHDYINIIKK HYVSLGVGIR PCFQAVFISL LSGLEEDVDE SSQEVYHLLD DLVKVLNDEK
     FAWGCIWSTI LSFPSQRPGA LAYLLRVCNN LAEEDIQTRV IQPDSGLVVR SFAAAISDND
     ILVQRGYMDA LLNYFPIQST FYKDVKPFDL KLLHMSVASI VLRNDLSLNR RFYAWLMGLS
     KDTELSISDS SITVDENTLQ QNMAIFFEGV KDLLSSKNSL MSFYKAFRIL YALSDRRPLF
     TIVESQILPC VLHSYETLTN VFHRDDSKHL YESAVDHGRR LIMKFSDSEL HTFLFHCVNK
     IVANTTENSD SAEAVKFILD SQNFFFESIN TEYSFIIFTN LLMHLEKTSP NSDVDGVSMT
     ILTICKILLN NFDWNFFNYN NSAIDSYAKC TLNLDSDFEN GILTYEILYK KCKCSLLSLL
     KQYIKDSHVH HEVLLISLNL IKEASDTEFE NEFLDLSLQG FKDNSWSFQT LGSFVKQLPS
     RILINSTACV NVILDRIWCE LCMFSYFREE ELLSVIWTLQ EKLQTRIIES YFSTCIVKEQ
     LELRAPTIYY TPFYNLLKKS AQQSLFHFVF DRPLLLLLNS LLEDESGRDY TAMMNWINAS
     SSLQLRVLEL MTENLLSLSP NLTSVNSLET AMTRYNINED QRNSEASRCV YFLKLCTRII
     SYFQDLHPKE GRLKSAKQVE ELCLVTWADA LLIQKKSLTY SSFLAFLVKL CLDIVLTPQN
     IKTSTDVYII QTWALRLLYQ ITSIWENPLK FESSLIVGLF ALVQEVERSP SSTYRSFILS
     LLQMLEFLLS RLDGTIDLSS EQHYLLSNFV LVGMLNDDPG LSPKWLHAIK KLLPLLLQNL
     QLLMVNPIQS LCKFVHSFLD QHESMYLKYP DPVKDYACMD VFIAKLKMLS ELVSAALLEF
     TYSPGPKKSN LEANGIIGNV ISGVFAAESS GVSIDVNKRL SMLLTMQDAL QTLFLSYSWH
     IRSSYADKTS KVFMNDSSVL KEASLSGLKE FYFCEPLECV ETLVQIYLEN NVECCQCIWD
     IFSFLSDSEP QYIVKQLVSS FFAREGIASY AGPSSLTAKI TQLDILCCMS DFVSRVEGEN
     TSKIFTEISK FVREIISSSN SFKNYLLVCL RMLLEVAKNV NTYCESRQQK DFIDLMGKTL
     SSVLFHAGKS SDPNLTVDFL AYHKAAADTF EVAKTQKKTS SVYLFVKYLD PSLLDFFCSE
     FVPKITELSK EEDKLVAWAT SIVNVFITPL VKARTFPESL TTYHLDLLLV LSKHPFLSKS
     WRRDFWEIFN DNSLFRFDID QLRKLSPVIY TALYQEISRL NDLITKSDLG VTTLFTSRDT
     QLGARQSNIC RITILMLSSP RDFFLPSLPP LIDLVKRLIT SDPEGVLKKD LFLFIRALAL
     RTSSKHLLPL WPIVVSELLI IFKSYCMPNV AISKETLLDA CRLLDFLTAL KLEEFALHEW
     VVMLSPLDAV YWSGKTSRKS LVQKVSERLQ EQASEKDDKS SVESEHSILT STTRTPSLGI
     YTTDAQLRNF LNRISIDAYE ESYSFSTIDI QSFENSIYRE VLQRFSNAPL SPFSSIKAPS
     SLAGSSN