DP2NB_HUMAN
ID DP2NB_HUMAN Reviewed; 123 AA.
AC A0A0U1RQF7;
DT 18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT 17-FEB-2016, sequence version 1.
DT 03-AUG-2022, entry version 31.
DE RecName: Full=DPEP2 neighbor protein;
GN Name=DPEP2NB {ECO:0000312|HGNC:HGNC:52385};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.;
RT "Cloning of human full open reading frames in Gateway(TM) system entry
RT vector (pDONR201).";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- INTERACTION:
CC A0A0U1RQF7; Q9H6L4: ARMC7; NbExp=3; IntAct=EBI-18398199, EBI-742909;
CC A0A0U1RQF7; Q9NPB3: CABP2; NbExp=3; IntAct=EBI-18398199, EBI-12011224;
CC A0A0U1RQF7; P27658: COL8A1; NbExp=3; IntAct=EBI-18398199, EBI-747133;
CC A0A0U1RQF7; O43559: FRS3; NbExp=3; IntAct=EBI-18398199, EBI-725515;
CC A0A0U1RQF7; Q63ZY3: KANK2; NbExp=3; IntAct=EBI-18398199, EBI-2556193;
CC A0A0U1RQF7; P41271-2: NBL1; NbExp=3; IntAct=EBI-18398199, EBI-12135485;
CC A0A0U1RQF7; Q9BUZ4: TRAF4; NbExp=3; IntAct=EBI-18398199, EBI-3650647;
CC A0A0U1RQF7; Q86VK4-3: ZNF410; NbExp=3; IntAct=EBI-18398199, EBI-11741890;
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DR EMBL; BX107720; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AC040162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC130462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471092; EAW83205.1; -; Genomic_DNA.
DR CCDS; CCDS82001.1; -.
DR RefSeq; NP_001269371.1; NM_001282442.1.
DR AlphaFoldDB; A0A0U1RQF7; -.
DR IntAct; A0A0U1RQF7; 8.
DR BioMuta; ENSG00000263201; -.
DR MassIVE; A0A0U1RQF7; -.
DR PeptideAtlas; A0A0U1RQF7; -.
DR DNASU; 100131303; -.
DR Ensembl; ENST00000574912.1; ENSP00000488973.1; ENSG00000263201.1.
DR GeneID; 100131303; -.
DR KEGG; hsa:100131303; -.
DR MANE-Select; ENST00000574912.1; ENSP00000488973.1; NM_001282442.2; NP_001269371.1.
DR CTD; 100131303; -.
DR GeneCards; DPEP2NB; -.
DR HGNC; HGNC:52385; DPEP2NB.
DR HPA; ENSG00000263201; Tissue enriched (testis).
DR neXtProt; NX_A0A0U1RQF7; -.
DR VEuPathDB; HostDB:ENSG00000263201; -.
DR GeneTree; ENSGT00740000117161; -.
DR OMA; SFVPWEG; -.
DR OrthoDB; 1563072at2759; -.
DR PathwayCommons; A0A0U1RQF7; -.
DR SignaLink; A0A0U1RQF7; -.
DR BioGRID-ORCS; 100131303; 5 hits in 76 CRISPR screens.
DR GenomeRNAi; 100131303; -.
DR Pharos; A0A0U1RQF7; Tdark.
DR PRO; PR:A0A0U1RQF7; -.
DR Proteomes; UP000005640; Chromosome 16.
DR RNAct; A0A0U1RQF7; protein.
DR Bgee; ENSG00000263201; Expressed in tibialis anterior and 14 other tissues.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..123
FT /note="DPEP2 neighbor protein"
FT /id="PRO_0000444871"
FT REGION 67..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 123 AA; 13402 MW; 06D1534BBCD5B55D CRC64;
MTDRILYIVS NMSSVPWEGS AAAAVPATSP PTPGHYHVLY RGCGETQVGW HGETYCLVGG
YRVHGDAPLA TPTKAEAEKP APRRAPKRRQ ATIESDKDLG CSSPKIRRLE HRGRRLTPQK
LAG