DP87_DICDI
ID DP87_DICDI Reviewed; 555 AA.
AC Q04503; Q54RC6;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Prespore protein Dp87;
DE Flags: Precursor;
GN Name=cotD; Synonyms=Dp87; ORFNames=DDB_G0283149;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=AX3;
RX PubMed=8404532; DOI=10.1242/dev.117.4.1299;
RA Ozaki T., Nakao H., Orii H., Morio T., Takeuchi I., Tasaka M.;
RT "Developmental regulation of transcription of a novel prespore-specific
RT gene (Dp87) in Dictyostelium discoideum.";
RL Development 117:1299-1308(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Spore wall. Note=Stored in prespore vacuoles
CC until it is discharged into the interspace of spores during spore
CC formation.
CC -!- INDUCTION: By exogenous cAMP, repressed by DIF.
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DR EMBL; D13973; BAA03083.1; -; Genomic_DNA.
DR EMBL; AAFI02000051; EAL65813.1; -; Genomic_DNA.
DR RefSeq; XP_639219.1; XM_634127.1.
DR AlphaFoldDB; Q04503; -.
DR STRING; 44689.DDB0191431; -.
DR PaxDb; Q04503; -.
DR EnsemblProtists; EAL65813; EAL65813; DDB_G0283149.
DR GeneID; 8623992; -.
DR KEGG; ddi:DDB_G0283149; -.
DR dictyBase; DDB_G0283149; cotD.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_507566_0_0_1; -.
DR InParanoid; Q04503; -.
DR OMA; EWICAVP; -.
DR PhylomeDB; Q04503; -.
DR PRO; PR:Q04503; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0031160; C:spore wall; IDA:dictyBase.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEP:dictyBase.
DR InterPro; IPR007643; Dict_spore_N.
DR InterPro; IPR003645; Fol_N.
DR Pfam; PF04562; Dicty_spore_N; 1.
DR SMART; SM00274; FOLN; 8.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Repeat; Signal; Sporulation.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..555
FT /note="Prespore protein Dp87"
FT /id="PRO_0000032667"
FT DOMAIN 27..144
FT /note="DSCP-N"
FT DOMAIN 148..170
FT /note="Follistatin-like 1"
FT DOMAIN 175..197
FT /note="Follistatin-like 2"
FT DOMAIN 209..231
FT /note="Follistatin-like 3"
FT DOMAIN 240..262
FT /note="Follistatin-like 4"
FT DOMAIN 276..298
FT /note="Follistatin-like 5"
FT DOMAIN 304..327
FT /note="Follistatin-like 6"
FT DOMAIN 332..354
FT /note="Follistatin-like 7"
FT DOMAIN 362..384
FT /note="Follistatin-like 8"
FT REGION 454..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 103
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 306
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 418
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 54
FT /note="G -> C (in Ref. 1; BAA03083)"
FT /evidence="ECO:0000305"
FT CONFLICT 196
FT /note="C -> L (in Ref. 1; BAA03083)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 555 AA; 58618 MW; 60DA2CFA5123A149 CRC64;
MRILYLASLL FLITLYLSPT FGWGGGRDCE SHRSEYTCKS DRSCAYLPFV SCCGKKEFFC
VNRDHRNCCD DLSCAKNTRT GEIFEIWSSC KPHRDFVPYH SPNTTTCESL GCEARGMECE
WVESSPCYGT SCCPRIPRCV GHHGGGHKCD RMRCPEGFYC EEQGGSACCV PHHDGCGNIQ
CPWGHYCVNE HGKCRCVPHR PPPRPPVDQC RNQHCPHGYS CRVIKGCATC VRDARPPHNL
CRGFGCPEGS HCEVLEKHPV CVRNHVPPHP PPPPQICGSV NCGPGYICTI INGHPTCIRG
DGYLCNQTRC PHDYQCETIS TNIVKCSPKN DECKWHRCPP GSSCFNSRNG PHCLANNVFP
QLCKVTQCPT DFSCKMIRGN PTCIKARPPV PPPHCSTCAE LSSACNHVGM ICIQVPSNCT
NTRFPCCPSH PICIHPSTTA ASTIATTAST VATTTSATTA GTTTGGTTTG GSTSDSSAAS
SADSSAASSS PSSSAASSAA SSEPSSSAAS SSAPSSASSS APSSASSSAP SSSASSSAAS
SAASSESSES SSATS
