ID   DPA5B_MOUSE             Reviewed;         119 AA.
AC   P85965;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Developmental pluripotency-associated protein 5B/5C;
GN   Name=Dppa5b {ECO:0000312|MGI:MGI:3765340};
GN   and
GN   Name=Dppa5c {ECO:0000312|MGI:MGI:3765342};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000305}
RP   IDENTIFICATION.
RX   PubMed=17913455; DOI=10.1016/j.ygeno.2007.06.003;
RA   Pierre A., Gautier M., Callebaut I., Bontoux M., Jeanpierre E.,
RA   Pontarotti P., Monget P.;
RT   "Atypical structure and phylogenomic evolution of the new eutherian
RT   oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family.";
RL   Genomics 90:583-594(2007).
CC   -!- FUNCTION: Involved in the maintenance of embryonic stem (ES) cell
CC       pluripotency. Dispensable for self-renewal of pluripotent ES cells and
CC       establishment of germ cells. Associates with specific target mRNAs (By
CC       similarity). {ECO:0000250|UniProtKB:Q9CQS7}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9CQS7}.
CC   -!- SIMILARITY: Belongs to the KHDC1 family. {ECO:0000255}.
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DR   EMBL; AC138587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P85965; -.
DR   SMR; P85965; -.
DR   PeptideAtlas; P85965; -.
DR   PRIDE; P85965; -.
DR   MGI; MGI:3765340; Dppa5b.
DR   MGI; MGI:3765342; Dppa5c.
DR   InParanoid; P85965; -.
DR   PRO; PR:P85965; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P85965; protein.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   Gene3D; 3.30.1370.10; -; 1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR031952; MOEP19_KH-like.
DR   Pfam; PF16005; MOEP19; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Developmental protein; Reference proteome; RNA-binding.
FT   CHAIN           1..119
FT                   /note="Developmental pluripotency-associated protein 5B/5C"
FT                   /id="PRO_0000347270"
FT   DOMAIN          24..86
FT                   /note="KH; atypical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   119 AA;  13948 MW;  24411D4FC3027001 CRC64;
     MMVTLVTRKD IPPWVKVPED LTDPEVFQVQ SLVLKYLFGP QGSRMSHIEQ VSQAMFELKN
     LESPEELIEV FIYGYQSIKV RAKWLLQSMA ERYHLRQQKR PSLTTFWEFG GPDVSLKEC