ID   DPB3_CANGA              Reviewed;         255 AA.
AC   Q6FXJ8;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=DNA polymerase epsilon subunit C;
DE   AltName: Full=DNA polymerase II subunit C;
GN   Name=DPB3; OrderedLocusNames=CAGL0B03355g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: As accessory component of the DNA polymerase epsilon (DNA
CC       polymerase II) participates in chromosomal DNA replication.
CC       {ECO:0000250|UniProtKB:P27344}.
CC   -!- SUBUNIT: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3
CC       and DPB4 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- MISCELLANEOUS: In eukaryotes there are five DNA polymerases: alpha,
CC       beta, gamma, delta, and epsilon which are responsible for different
CC       reactions of DNA synthesis.
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DR   EMBL; CR380948; CAG58017.1; -; Genomic_DNA.
DR   RefSeq; XP_445117.1; XM_445117.1.
DR   AlphaFoldDB; Q6FXJ8; -.
DR   SMR; Q6FXJ8; -.
DR   STRING; 5478.XP_445117.1; -.
DR   EnsemblFungi; CAG58017; CAG58017; CAGL0B03355g.
DR   GeneID; 2886501; -.
DR   KEGG; cgr:CAGL0B03355g; -.
DR   CGD; CAL0127826; CAGL0B03355g.
DR   VEuPathDB; FungiDB:CAGL0B03355g; -.
DR   eggNOG; KOG1658; Eukaryota.
DR   HOGENOM; CLU_1089889_0_0_1; -.
DR   InParanoid; Q6FXJ8; -.
DR   OMA; SNAAFMA; -.
DR   Proteomes; UP000002428; Chromosome B.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..255
FT                   /note="DNA polymerase epsilon subunit C"
FT                   /id="PRO_0000208345"
FT   REGION          109..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..155
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..222
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..255
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   255 AA;  28353 MW;  E1A115813EB10909 CRC64;
     MSMSEEEKMV LQQKIRDRTP KLPISKVKRI GKVDPESILT SNMAYVATAF ATELFVQSFV
     EQALFGAQLR RGKKKAGLRL TNDALVECVR NRDDYIFLED VVRHIEKPKT SSGLHKLSAK
     PVGQGQEAEQ KDASMEEDIP EEDLQEDDEM DVDETEPAER PAASKASDVN KASASAKSIL
     SAFKYAPESA PQIHGSTQTE EDEGDEKEED EDEEEEIDPE VQTQLQEVEK MNVVADLDEE
     SEVSSDEDEA SADDG