ID   DPB4_CANGA              Reviewed;         191 AA.
AC   Q6FXD0;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=DNA polymerase epsilon subunit D;
DE   AltName: Full=DNA polymerase II subunit D;
GN   Name=DPB4; OrderedLocusNames=CAGL0B01903g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: As accessory component of the DNA polymerase epsilon (DNA
CC       polymerase II) participates in chromosomal DNA replication.
CC       {ECO:0000250|UniProtKB:Q04603}.
CC   -!- SUBUNIT: Heterotetramer. Consists of four subunits: POL2, DPB2, DPB3
CC       and DPB4 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- MISCELLANEOUS: In eukaryotes there are five DNA polymerases: alpha,
CC       beta, gamma, delta, and epsilon which are responsible for different
CC       reactions of DNA synthesis.
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DR   EMBL; CR380948; CAG57952.1; -; Genomic_DNA.
DR   RefSeq; XP_445052.1; XM_445052.1.
DR   AlphaFoldDB; Q6FXD0; -.
DR   SMR; Q6FXD0; -.
DR   STRING; 5478.XP_445052.1; -.
DR   EnsemblFungi; CAG57952; CAG57952; CAGL0B01903g.
DR   GeneID; 2886549; -.
DR   KEGG; cgr:CAGL0B01903g; -.
DR   CGD; CAL0127082; CAGL0B01903g.
DR   VEuPathDB; FungiDB:CAGL0B01903g; -.
DR   eggNOG; KOG0870; Eukaryota.
DR   HOGENOM; CLU_087036_1_0_1; -.
DR   InParanoid; Q6FXD0; -.
DR   OMA; ALDHIGH; -.
DR   Proteomes; UP000002428; Chromosome B.
DR   GO; GO:0008623; C:CHRAC; IEA:EnsemblFungi.
DR   GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:EnsemblFungi.
DR   GO; GO:0043596; C:nuclear replication fork; IEA:EnsemblFungi.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:EnsemblFungi.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0008310; F:single-stranded DNA 3'-5' exodeoxyribonuclease activity; IEA:EnsemblFungi.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:EnsemblFungi.
DR   GO; GO:0042276; P:error-prone translesion synthesis; IEA:EnsemblFungi.
DR   GO; GO:0006272; P:leading strand elongation; IEA:EnsemblFungi.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..191
FT                   /note="DNA polymerase epsilon subunit D"
FT                   /id="PRO_0000191749"
FT   REGION          154..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   191 AA;  21864 MW;  4733CE7720019C95 CRC64;
     MPPKGWRKDA QGNYPTTSYM KEQENVTMQD LLFPRSVIMA LAKEVPEMQQ QQVQVQAAEK
     GEPVEKTPAK KLVVTKDASM ALQHSATVFV NHLLMYAREL AKEQDRRSCN VDDILNALEH
     MGHPGLKPLV ANRLDDYQEA LEWKKQLKAQ LQILNGEAEE EPNELGTYDH DNETDDEEIR
     DEPEKKLKVE P