ID   DPCKG_HALWD             Reviewed;         186 AA.
AC   Q18KI2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=GTP-dependent dephospho-CoA kinase {ECO:0000255|HAMAP-Rule:MF_00590};
DE            EC=2.7.1.- {ECO:0000255|HAMAP-Rule:MF_00590};
DE   AltName: Full=Dephospho-coenzyme A kinase {ECO:0000255|HAMAP-Rule:MF_00590};
DE            Short=DPCK {ECO:0000255|HAMAP-Rule:MF_00590};
GN   OrderedLocusNames=HQ_1339A;
OS   Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16790 / HBSQ001;
RX   PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA   Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F.,
RA   Pfeiffer F., Oesterhelt D.;
RT   "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT   limits of water activity.";
RL   BMC Genomics 7:169-169(2006).
CC   -!- FUNCTION: Catalyzes the GTP-dependent phosphorylation of the 3'-
CC       hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
CC       {ECO:0000255|HAMAP-Rule:MF_00590}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3'-dephospho-CoA + GTP = CoA + GDP + H(+);
CC         Xref=Rhea:RHEA:61156, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57328, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00590};
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00590}.
CC   -!- SIMILARITY: Belongs to the GTP-dependent DPCK family.
CC       {ECO:0000255|HAMAP-Rule:MF_00590}.
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DR   EMBL; AM180088; CAJ51467.1; -; Genomic_DNA.
DR   RefSeq; WP_011570624.1; NC_008212.1.
DR   AlphaFoldDB; Q18KI2; -.
DR   STRING; 362976.HQ_1339A; -.
DR   EnsemblBacteria; CAJ51467; CAJ51467; HQ_1339A.
DR   GeneID; 4192259; -.
DR   KEGG; hwa:HQ_1339A; -.
DR   eggNOG; arCOG04076; Archaea.
DR   HOGENOM; CLU_120795_0_0_2; -.
DR   OMA; AIYDHKT; -.
DR   UniPathway; UPA00241; -.
DR   Proteomes; UP000001975; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   HAMAP; MF_00590; Dephospho_CoA_kinase_GTP_dep; 1.
DR   InterPro; IPR007164; GTP-dep_dephospho-CoA_kin.
DR   PANTHER; PTHR40732; PTHR40732; 1.
DR   Pfam; PF04019; DUF359; 1.
DR   PIRSF; PIRSF006533; UCP006533; 1.
PE   3: Inferred from homology;
KW   Coenzyme A biosynthesis; Kinase; Reference proteome; Transferase.
FT   CHAIN           1..186
FT                   /note="GTP-dependent dephospho-CoA kinase"
FT                   /id="PRO_0000380049"
SQ   SEQUENCE   186 AA;  20117 MW;  97ADFCEAA33215A1 CRC64;
     MDRLPLELPS SLRQEFKSPF GPVYTDVTQF LTDAGRPIIA VGDIVTYHLQ TVDYTPAVAV
     IDGQTKRESV DETVKAALSK HNKRIDVENQ PGTISIALLE ALQTAVETPE SVMIVVDGEE
     DLATLPAVLV ARPGGTVVYG QPDQGMVRIA VTPETKITMS RLLKRMDGDA AAAFDRLGVD
     RSGDKK