ID   DPCKG_KORCO             Reviewed;         167 AA.
AC   B1L6M9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=GTP-dependent dephospho-CoA kinase {ECO:0000255|HAMAP-Rule:MF_00590};
DE            EC=2.7.1.- {ECO:0000255|HAMAP-Rule:MF_00590};
DE   AltName: Full=Dephospho-coenzyme A kinase {ECO:0000255|HAMAP-Rule:MF_00590};
DE            Short=DPCK {ECO:0000255|HAMAP-Rule:MF_00590};
GN   OrderedLocusNames=Kcr_1362;
OS   Korarchaeum cryptofilum (strain OPF8).
OC   Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum.
OX   NCBI_TaxID=374847;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OPF8;
RX   PubMed=18535141; DOI=10.1073/pnas.0801980105;
RA   Elkins J.G., Podar M., Graham D.E., Makarova K.S., Wolf Y., Randau L.,
RA   Hedlund B.P., Brochier-Armanet C., Kunin V., Anderson I., Lapidus A.,
RA   Goltsman E., Barry K., Koonin E.V., Hugenholtz P., Kyrpides N., Wanner G.,
RA   Richardson P., Keller M., Stetter K.O.;
RT   "A korarchaeal genome reveals new insights into the evolution of the
RT   Archaea.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:8102-8107(2008).
CC   -!- FUNCTION: Catalyzes the GTP-dependent phosphorylation of the 3'-
CC       hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
CC       {ECO:0000255|HAMAP-Rule:MF_00590}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3'-dephospho-CoA + GTP = CoA + GDP + H(+);
CC         Xref=Rhea:RHEA:61156, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57328, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00590};
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00590}.
CC   -!- SIMILARITY: Belongs to the GTP-dependent DPCK family.
CC       {ECO:0000255|HAMAP-Rule:MF_00590}.
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DR   EMBL; CP000968; ACB08108.1; -; Genomic_DNA.
DR   RefSeq; WP_012310005.1; NC_010482.1.
DR   AlphaFoldDB; B1L6M9; -.
DR   STRING; 374847.Kcr_1362; -.
DR   PRIDE; B1L6M9; -.
DR   EnsemblBacteria; ACB08108; ACB08108; Kcr_1362.
DR   GeneID; 6094639; -.
DR   KEGG; kcr:Kcr_1362; -.
DR   eggNOG; arCOG04076; Archaea.
DR   HOGENOM; CLU_120795_0_0_2; -.
DR   InParanoid; B1L6M9; -.
DR   OMA; AIYDHKT; -.
DR   PhylomeDB; B1L6M9; -.
DR   UniPathway; UPA00241; -.
DR   Proteomes; UP000001686; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   HAMAP; MF_00590; Dephospho_CoA_kinase_GTP_dep; 1.
DR   InterPro; IPR007164; GTP-dep_dephospho-CoA_kin.
DR   PANTHER; PTHR40732; PTHR40732; 1.
DR   Pfam; PF04019; DUF359; 1.
PE   3: Inferred from homology;
KW   Coenzyme A biosynthesis; Kinase; Reference proteome; Transferase.
FT   CHAIN           1..167
FT                   /note="GTP-dependent dephospho-CoA kinase"
FT                   /id="PRO_0000380052"
SQ   SEQUENCE   167 AA;  18707 MW;  F0D3743AD496A398 CRC64;
     MLFDLKLLED KRGKVSEIKG SIIKSLDILE NKRIISVGDR VTRELLGSGR RPEVAIIDLK
     ERREMNCSTI FYLDDYLILV ARNPAGTLMR EAWLKVRKAI EISLSGKNAA VIVDGEEDLL
     GFPAIILPPE GWVMVYGQPG VGMVSVNIDR KAREEAMNLL QEAFLPI