ID   DPIA_SHIFL              Reviewed;         226 AA.
AC   P0AEF7; Q54149;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Transcriptional regulatory protein DpiA;
GN   Name=dpiA; Synonyms=criR;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HW1002 / Serotype 1b;
RA   Qi M.S., Yoshikura H., Watanabe H.;
RL   Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Positive transcriptional regulator for increasing the
CC       expression of ipa genes.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- PTM: Phosphorylated by DpiB. {ECO:0000250}.
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DR   EMBL; U29654; AAA86117.1; -; Genomic_DNA.
DR   RefSeq; WP_000126500.1; NZ_SPPU01000012.1.
DR   AlphaFoldDB; P0AEF7; -.
DR   SMR; P0AEF7; -.
DR   GeneID; 66671105; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR024187; Sig_transdc_resp-reg_cit/mal.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR028141; Transcriptional_reg_dom.
DR   PANTHER; PTHR45526; PTHR45526; 1.
DR   Pfam; PF12431; CitT; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PIRSF; PIRSF006171; RR_citrat_malat; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..226
FT                   /note="Transcriptional regulatory protein DpiA"
FT                   /id="PRO_0000081071"
FT   DOMAIN          6..122
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DNA_BIND        180..199
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         57
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   226 AA;  25453 MW;  2A47279EED145743 CRC64;
     MTAPLTLLIV EDETPLAEMH AEYIRHIPGF SQILLAGNLA QARMMIERFK PGLILLDNYL
     PDGRGINLLH ELVQAHYPGD VVFTTAASDM ETVSEAVRCG VFDYLIKPIA YERLGQTLTR
     FRQRKHMLES IDSASQKQID EMFNAYARGE PKDELPTGID PLTLNAVRKL FKEPGVQHTA
     ETVAQALTIS RTTARRYLEY CASRHLIIAE IVHGKVGRPQ RIYHSG