ID   DPOD2_ARATH             Reviewed;         440 AA.
AC   O48520; Q8L781;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 2.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=DNA polymerase delta small subunit;
DE            EC=2.7.7.7;
GN   Name=POLD2; OrderedLocusNames=At2g42120; ORFNames=T24P15.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The function of the small subunit is not yet clear.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC   -!- SUBUNIT: Heterodimer with subunits of 125 kDa and 50 kDa.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences.;
CC       Name=1;
CC         IsoId=O48520-1; Sequence=Displayed;
CC   -!- SIMILARITY: Belongs to the DNA polymerase delta/II small subunit
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB88640.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC002561; AAB88640.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC10072.1; -; Genomic_DNA.
DR   EMBL; AY136418; AAM97084.1; -; mRNA.
DR   EMBL; BT008753; AAP49515.1; -; mRNA.
DR   EMBL; AK221655; BAD95325.1; -; mRNA.
DR   PIR; T00922; T00922.
DR   RefSeq; NP_973664.1; NM_201935.3. [O48520-1]
DR   AlphaFoldDB; O48520; -.
DR   SMR; O48520; -.
DR   BioGRID; 4149; 2.
DR   IntAct; O48520; 1.
DR   STRING; 3702.AT2G42120.1; -.
DR   PaxDb; O48520; -.
DR   PRIDE; O48520; -.
DR   ProteomicsDB; 241251; -. [O48520-1]
DR   EnsemblPlants; AT2G42120.2; AT2G42120.2; AT2G42120. [O48520-1]
DR   GeneID; 818812; -.
DR   Gramene; AT2G42120.2; AT2G42120.2; AT2G42120. [O48520-1]
DR   KEGG; ath:AT2G42120; -.
DR   Araport; AT2G42120; -.
DR   eggNOG; KOG2732; Eukaryota.
DR   HOGENOM; CLU_021763_0_0_1; -.
DR   InParanoid; O48520; -.
DR   OMA; DPANFML; -.
DR   PhylomeDB; O48520; -.
DR   PRO; PR:O48520; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O48520; baseline and differential.
DR   Genevisible; O48520; AT.
DR   GO; GO:0043625; C:delta DNA polymerase complex; IBA:GO_Central.
DR   GO; GO:0042575; C:DNA polymerase complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IBA:GO_Central.
DR   CDD; cd07387; MPP_PolD2_C; 1.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR040663; DNA_pol_D_N.
DR   InterPro; IPR024826; DNA_pol_delta/II_ssu.
DR   InterPro; IPR041863; PolD2_C.
DR   PANTHER; PTHR10416; PTHR10416; 1.
DR   Pfam; PF18018; DNA_pol_D_N; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; DNA replication; DNA-directed DNA polymerase;
KW   Nucleotidyltransferase; Nucleus; Reference proteome; Transferase.
FT   CHAIN           1..440
FT                   /note="DNA polymerase delta small subunit"
FT                   /id="PRO_0000096171"
SQ   SEQUENCE   440 AA;  49410 MW;  790D3E7450C0BE50 CRC64;
     MEIDSEKIHE RKQSDYNSLD ERFEIQKEMY RGQQYSQIYF ARLHLMRTLL YSLAPTWKSH
     LPVCKVLGLE KGKECIIVGT LFKHMKLKPC VLDEYSKERS VTPLVKPHNF MHPDDNLILE
     DESGRVKLAG SALSPAIYVT GVVVALHGKE TNAGEFFVED VLEAGLPPQI ERPIDLQEDK
     YVVLLSGLCI GSKSANPLQF QLLVDHITGH LGDEEEQGLA AQIVHVVIAG NSFEFPRKLI
     NGQNLASKDQ STLYEPIKEL DIMLSQIAAG VSVDIMPGTN DPANFALPQQ PLNRCLFPGS
     SPYNTFRSCT NPHSFDVDNI RFLGTSGQNI DDLGKYSEAK SKLDFVERTL RWRHLAPTAP
     NTLGCYPFTD RDPFLIETCP HVYFVGNQDK YDNRLIKGSE GQLVRLICIP KFCETGIAVA
     VNLRNLECHT LSFSTQINQS