ID   DPOL_IIV6               Reviewed;        1273 AA.
AC   Q9QSK2; Q9DIE2;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   29-SEP-2021, entry version 97.
DE   RecName: Full=DNA polymerase 037L;
DE            EC=2.7.7.7;
GN   Name=DPOL; ORFNames=IIV6-037L;
OS   Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Betairidovirinae; Iridovirus.
OX   NCBI_TaxID=176652;
OH   NCBI_TaxID=6997; Acheta domesticus (House cricket).
OH   NCBI_TaxID=168631; Chilo suppressalis (Asiatic rice borer moth).
OH   NCBI_TaxID=6999; Gryllus bimaculatus (Two-spotted cricket).
OH   NCBI_TaxID=58607; Gryllus campestris.
OH   NCBI_TaxID=7108; Spodoptera frugiperda (Fall armyworm).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11448171; DOI=10.1006/viro.2001.0963;
RA   Jakob N.J., Mueller K., Bahr U., Darai G.;
RT   "Analysis of the first complete DNA sequence of an invertebrate iridovirus:
RT   coding strategy of the genome of Chilo iridescent virus.";
RL   Virology 286:182-196(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 636-910.
RX   PubMed=11086137; DOI=10.1099/0022-1317-81-12-3059;
RA   Stasiak K., Demattei M.V., Federici B.A., Bigot Y.;
RT   "Phylogenetic position of the Diadromus pulchellus ascovirus DNA polymerase
RT   among viruses with large double-stranded DNA genomes.";
RL   J. Gen. Virol. 81:3059-3072(2000).
RN   [3]
RP   GENOME REANNOTATION.
RX   PubMed=17239238; DOI=10.1186/1743-422x-4-11;
RA   Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.;
RT   "Comparative genomic analysis of the family Iridoviridae: re-annotating and
RT   defining the core set of iridovirus genes.";
RL   Virol. J. 4:11-11(2007).
CC   -!- FUNCTION: DNA-directed DNA polymerase involved in viral DNA
CC       replication.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family. {ECO:0000305}.
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DR   EMBL; AF303741; AAD48150.1; -; Genomic_DNA.
DR   EMBL; AJ279816; CAC19195.1; -; Genomic_DNA.
DR   RefSeq; NP_149500.1; NC_003038.1.
DR   PRIDE; Q9QSK2; -.
DR   GeneID; 921680; -.
DR   KEGG; vg:921680; -.
DR   Proteomes; UP000001359; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.132.60; -; 2.
DR   Gene3D; 3.30.420.10; -; 2.
DR   Gene3D; 3.90.1600.10; -; 2.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR042087; DNA_pol_B_thumb.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF00136; DNA_pol_B; 2.
DR   Pfam; PF03104; DNA_pol_B_exo1; 1.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 2.
DR   SUPFAM; SSF56672; SSF56672; 1.
PE   3: Inferred from homology;
KW   Coiled coil; DNA replication; DNA-binding; DNA-directed DNA polymerase;
KW   Nucleotidyltransferase; Reference proteome; Transferase;
KW   Viral DNA replication.
FT   CHAIN           1..1273
FT                   /note="DNA polymerase 037L"
FT                   /id="PRO_0000376943"
FT   COILED          679..837
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1273 AA;  147663 MW;  CC514AD83F7299A3 CRC64;
     MEKTMFAYSW HQTDDETKNW SKSKESLRIY GITDDGKTIC LIVNDFKPFV HVELPSSINW
     RQKIGGQPKV QKIMDYLNFI LGDLKPVKNR TIFIDKYKLY GSNYVQTSPG VFQRKKFPYL
     VLFFESRKHI KNLEYKLKNT VDVPGFGKIK LNVRETNVSP ILQLCVERNL PSAGWIGFKV
     EGRGALAGYG ELVEEKKKFT DCDEEYVISK NYIYSIDKHV PVKAKVMAWD IEVYSEDGNF
     PDAMKPGNVV FQISCIFFIV GTSYKQKYLL TLGDPLEYTT TPINEEGCGK DTIVCKFKTE
     EDLIIAFSSL QKREKPHITT GWNIFNFDTT FLLKRAKLHR CLPNFLLQGF PKDQLGKEKE
     IKWQSKAYGT TDLKFIDCEG ILCIDLMDVV QKEHKLDSYS LNFVAKHFLG SKKDDLKPKE
     IFICYREGIK KEVKNIVIHP LSNNLNIYLG KEEIMIENKK FKKPLKPFFR IQNTGKLVSD
     EDDSVFHVNY RGEVFSFLIA VHNEEKYEIK TVSEFNNYKN AYGTYTLSAQ KAMAKVGKYC
     VQDSVLVADI FEHLQTWLSF SEMSRTCTTP IMTIHVHGQQ VKFFNQVYKY CYDHKTVTDK
     ETYKVDEKER YRGAEVFDPV PGLKRNVVPL DFASLYPSLI IARNMCYSTF VDNDDIPDEM
     CHVMEWDDHV ACSHDPKVIR KNAITEELEK LKKIANAKKM YTQGTRTYKK MMCSYLVMEN
     TKEKTEMSKH LKDLDRENNE LLNIVNKQTP GYIESIKKKI SDLTSERSEI TKKLSKSVMC
     VSNRRYRFLK EPKGILPTII QNLLDARKNT RTEIKNYKSR LALLMEKENK SKEDIDEITS
     IENLLPILDK RQNSYKISAN SMYGATGVRV GALPFMPIAM CTTYMGRKSI VEVSQYLKEL
     GGRVVYGDTD SNYVTFDDVV DKNVKVGTEE FSREMKKLWN HAIEIAKTIS KKFDNPITLE
     FENAIYFKFL ILTKKRYMYY TCGKDGNILM DANGKPKMGQ RGVILSRRDN CKYMKDVYAN
     VIDKIFDEQS ENEILNGVVE KMLNLYTRQI EFTSCEKDEN YLKNLIVTKS VGDYGGDKAT
     FEPILGKNEK GEDKWKIGNY VVPLITDEII KTCGTNGLPM TQNEIKDWYL ERLPCQVQLE
     VKIKRRGHNK EEGQRLSYVV TDIGCKGKQS EKIESVEYFK THSKVLKLDY GYYIERLIEP
     LDQVFQAVFK NCQEKETIYS DNFRKTKLFS IFEKRGKHSQ ANFTKELHKL CSVTKPKLIN
     EIKSFSKPDL VFV