ID   DPOM_AGABT              Reviewed;         797 AA.
AC   P30322;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Probable DNA polymerase;
DE            EC=2.7.7.7;
DE   Flags: Fragment;
OS   Agaricus bitorquis (Pavement mushroom) (Psalliota bitorquis).
OG   Mitochondrion.
OG   Plasmid pEM.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricaceae; Agaricus.
OX   NCBI_TaxID=5343;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 24666 / Ag4 / CBS 507.73;
RX   PubMed=1879001; DOI=10.1007/bf00312742;
RA   Robison M.M., Royer J.C., Horgen P.A.;
RT   "Homology between mitochondrial DNA of Agaricus bisporus and an internal
RT   portion of a linear mitochondrial plasmid of Agaricus bitorquis.";
RL   Curr. Genet. 19:495-502(1991).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- MISCELLANEOUS: This DNA polymerase requires a protein as a primer.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family. {ECO:0000305}.
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DR   EMBL; X63075; CAA44800.1; -; Genomic_DNA.
DR   PIR; S28103; S28103.
DR   AlphaFoldDB; P30322; -.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 2.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR004868; DNA-dir_DNA_pol_B_mt/vir.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF03175; DNA_pol_B_2; 1.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
PE   3: Inferred from homology;
KW   DNA replication; DNA-binding; DNA-directed DNA polymerase; Mitochondrion;
KW   Nucleotidyltransferase; Plasmid; Transferase.
FT   CHAIN           <1..797
FT                   /note="Probable DNA polymerase"
FT                   /id="PRO_0000046550"
FT   NON_TER         1
SQ   SEQUENCE   797 AA;  91922 MW;  5C49EAF51FB7F927 CRC64;
     EFPKYDSITE LDVYCNQNNK SDVQMYNFIT KLESEYGNIT VTVYKGSKTI SNDKSILNEC
     ELYFVFNIGS NKRVVCLADN KTWDQSLKYW NSSKYPYPRW CDEYLTESEF VRSIGEYKFH
     VNNGTVKYWE KYYNFPDMVF NYSDKKHDLR IGSLDLETYG DNCFELGLGN LNVYAGGFAL
     NDGFKKLYYL NNDTELNSGE AIIKKMFGDL FDYIAEDRKA RNNYTIYAHN LGRFDSVFII
     RSLCSEGYKI NGQWIDNSIL YLKIVDSTRK LTIKLRDSIK LVPHSLDKAL SSNGCNISKG
     MFPHKFVNKD TLNYIGDKPD IKYYVDENKF NESKLKKYKS LPSILNLKKE CLNYLDKDIL
     GLLELMNKVS LTYFNEYKLN ITKFSTLPSI TLNIFGIRFY DDQNSIKMIN GPLSEFIRSS
     YFGGNSDIFV SGEERLVKNG YHYDMNSQYP YAMLQSMPTG NPVFSTNTDL NYYRNGFVFA
     RVTPPSKDTL VNLFIPRRSD DGSVICDRNT FYEFIPTPDL KQGLEYGYKF EVICGINFPD
     ACGNGELFSE FVNHFYEIKS SSTDLGQKYI AKLSLNSLYG KFGQKEREYS IRLLEKDKAK
     EIISKNHYSY MSEVSDNYTL IKSGGRLNSK LRRLYAEQAR INTINDDLLS SKFIKSRGIP
     SAVQISAMIS SYARTSINPF KNIPGNLAIA SNTDSLILRK PLEDHLIGKE IGKWKLEHKF
     KNGVFVKPKL YCYEDVDINE LIRKASGVTA SNLTYENFVE LVNGKDVLTN KELFRLNWET
     LNIEIVNINT KISGIKE