DPPB_ALKPO
ID DPPB_ALKPO Reviewed; 333 AA.
AC P94311; D3FZH0;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Dipeptide transport system permease protein DppB;
GN Name=dppB; OrderedLocusNames=BpOF4_05750;
OS Alkalihalophilus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4)
OS (Bacillus pseudofirmus).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalophilus.
OX NCBI_TaxID=398511;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9680333; DOI=10.1007/s007920050011;
RA Ito M., Cooperberg B., Krulwich T.A.;
RT "Diverse genes of alkaliphilic Bacillus firmus OF4 that complement K+-
RT uptake-deficient Escherichia coli include an ftsH homologue.";
RL Extremophiles 1:22-28(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2126 / JCM 17055 / OF4;
RX PubMed=21951522; DOI=10.1111/j.1462-2920.2011.02591.x;
RA Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J.,
RA Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B.,
RA Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G., Xue Y., Ma Y.,
RA Hu F.Z., Krulwich T.A.;
RT "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that
RT support the ability to grow in an external pH range from 7.5 to 11.4.";
RL Environ. Microbiol. 13:3289-3309(2011).
CC -!- FUNCTION: Probably part of the ABC transporter Dpp involved in
CC dipeptide transport. Responsible for the translocation of the substrate
CC across the membrane. {ECO:0000250|UniProtKB:P26903}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; U64514; AAB41689.1; -; Genomic_DNA.
DR EMBL; CP001878; ADC49212.1; -; Genomic_DNA.
DR PIR; T44636; T44636.
DR RefSeq; WP_012960485.1; NC_013791.2.
DR AlphaFoldDB; P94311; -.
DR SMR; P94311; -.
DR STRING; 398511.BpOF4_05750; -.
DR EnsemblBacteria; ADC49212; ADC49212; BpOF4_05750.
DR KEGG; bpf:BpOF4_05750; -.
DR eggNOG; COG0601; Bacteria.
DR HOGENOM; CLU_036879_0_0_9; -.
DR OMA; PDFWMGI; -.
DR OrthoDB; 1479518at2; -.
DR Proteomes; UP000001544; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR045621; BPD_transp_1_N.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF19300; BPD_transp_1_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Peptide transport; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..333
FT /note="Dipeptide transport system permease protein DppB"
FT /id="PRO_0000060001"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 95..324
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 333 AA; 37182 MW; E57D95F2681DDCF5 CRC64;
MLAYAMRRLL LLIPVLIGMT IVTFSIIHLI PGNPAQTILG EQASPQAIAD LEERLGLNEP
YWVQYGLYMK DLATGDLGTS LRTNKPIMEE IWPYLAATIE LTIFAMIFAI IIGVNAGIVS
AWKQNSWFDY LSMFIALVGV SMPIFWLALM EQWIFAQELG WLPAFGRDNP RDPIISTTGL
YVFDTIISGQ FDKTWESIKH LILPGIALGT IPMAIIARMT RSSMLEVLRS DYIRTVNAKG
SGQGVVIYKH ALKNALIPVL TVVGLQTGNL LGGAILTETI FSWPGIGRYI FEAINYRDYP
VIQSGILVVA TIFVLINLFV DLLYSYIDPR IKY
