ID   DPPB_HAEIN              Reviewed;         333 AA.
AC   P45096;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=Dipeptide transport system permease protein DppB {ECO:0000250|UniProtKB:P0AEF8};
GN   Name=dppB; OrderedLocusNames=HI_1187;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=8550458; DOI=10.1128/jb.178.2.396-402.1996;
RA   Preston A., Maskell D., Johnson A., Moxon E.R.;
RT   "Altered lipopolysaccharide characteristic of the I69 phenotype in
RT   Haemophilus influenzae results from mutations in a novel gene, isn.";
RL   J. Bacteriol. 178:396-402(1996).
CC   -!- FUNCTION: Part of the ABC transporter DppBCDF involved in dipeptide
CC       transport. Responsible for the translocation of the substrate across
CC       the membrane. {ECO:0000250|UniProtKB:P0AEF8}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. OppBC subfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC22840.1; -; Genomic_DNA.
DR   EMBL; U17295; AAA95972.1; -; Genomic_DNA.
DR   PIR; G64188; G64188.
DR   RefSeq; NP_439343.2; NC_000907.1.
DR   AlphaFoldDB; P45096; -.
DR   SMR; P45096; -.
DR   STRING; 71421.HI_1187; -.
DR   TCDB; 3.A.1.5.27; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; AAC22840; AAC22840; HI_1187.
DR   KEGG; hin:HI_1187; -.
DR   PATRIC; fig|71421.8.peg.1238; -.
DR   eggNOG; COG0601; Bacteria.
DR   HOGENOM; CLU_036879_0_0_6; -.
DR   OMA; WPGMGTF; -.
DR   PhylomeDB; P45096; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0071916; F:dipeptide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR045621; BPD_transp_1_N.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF19300; BPD_transp_1_N; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..333
FT                   /note="Dipeptide transport system permease protein DppB"
FT                   /id="PRO_0000060008"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        306..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          96..328
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   333 AA;  36788 MW;  57B3A0006CA6B3A7 CRC64;
     MFKFVFKRIL MVIPTFIAIT LITFALVHFI PGDPVEIMMG ERGLTAEVHQ QMMHQLGLDL
     PLYQQYFHYI GNVIQGDFGA SFRTQQPVLT EFFTLFPATA ELAFFALFWS LLGGIILGTI
     AAVKKDSWIS HTVTAASLTG YSMPIFWWGL ILILYVSPQL GLPQGGRLDN EFWIDTPTGF
     MLIDSWLSGV SGAFENAVKS LILPAIVLGT VPLAIITRMT RSAMLEVLGE DYIRTAKAKG
     LSYTRIVIVH ALRNALIPVV TVVGLIVAQL LSGAVLTETI FSWPGIGKWI IDAIQARDYP
     VLQGSVLIIA TIIIVVNLTV DLLYGVVNPR IRH