ID   DPPC_ALKPO              Reviewed;         304 AA.
AC   P94312; D3FZG9;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Dipeptide transport system permease protein DppC;
GN   Name=dppC; OrderedLocusNames=BpOF4_05745;
OS   Alkalihalophilus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4)
OS   (Bacillus pseudofirmus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalophilus.
OX   NCBI_TaxID=398511;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9680333; DOI=10.1007/s007920050011;
RA   Ito M., Cooperberg B., Krulwich T.A.;
RT   "Diverse genes of alkaliphilic Bacillus firmus OF4 that complement K+-
RT   uptake-deficient Escherichia coli include an ftsH homologue.";
RL   Extremophiles 1:22-28(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2126 / JCM 17055 / OF4;
RX   PubMed=21951522; DOI=10.1111/j.1462-2920.2011.02591.x;
RA   Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J.,
RA   Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B.,
RA   Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G., Xue Y., Ma Y.,
RA   Hu F.Z., Krulwich T.A.;
RT   "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that
RT   support the ability to grow in an external pH range from 7.5 to 11.4.";
RL   Environ. Microbiol. 13:3289-3309(2011).
CC   -!- FUNCTION: Probably part of the ABC transporter Dpp involved in
CC       dipeptide transport. Responsible for the translocation of the substrate
CC       across the membrane. {ECO:0000250|UniProtKB:P26904}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. OppBC subfamily. {ECO:0000305}.
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DR   EMBL; U64514; AAB41690.1; -; Genomic_DNA.
DR   EMBL; CP001878; ADC49211.1; -; Genomic_DNA.
DR   PIR; T44637; T44637.
DR   RefSeq; WP_012960484.1; NC_013791.2.
DR   AlphaFoldDB; P94312; -.
DR   STRING; 398511.BpOF4_05745; -.
DR   EnsemblBacteria; ADC49211; ADC49211; BpOF4_05745.
DR   KEGG; bpf:BpOF4_05745; -.
DR   eggNOG; COG1173; Bacteria.
DR   HOGENOM; CLU_028518_1_1_9; -.
DR   OMA; VHMRESA; -.
DR   OrthoDB; 1734230at2; -.
DR   Proteomes; UP000001544; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR025966; OppC_N.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF12911; OppC_N; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Peptide transport; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..304
FT                   /note="Dipeptide transport system permease protein DppC"
FT                   /id="PRO_0000060002"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          102..291
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   304 AA;  33144 MW;  F27255DBFCB71FE2 CRC64;
     MKTEHAKPLM TPEPNSPPPE DQYTAVSPWR EAFKQLKKNK LAIVGLIIIT SFILIAIFAP
     LLTSSSYAET NPSNRLQGPS AEHWFGTDDF GRDIFTRIVY GARLSLQVGF FAVTGALIFG
     TTLGLIAGYY GRWIDMLISR IFDIMLAFPS ILLAIAIVAI LGPSLQNALI AIAIVNVPIF
     GRLVRSKVIS LREEEFIMAA KAQGMKNGRI IFHHILPNSL APIIVQATLG FGTAILEAAA
     LGFLGLGAQA PMPEWGKMLS DSRQFIQSAP WTVLFPGFSI MLVVLGFNMI GDGLRDALDP
     KMKS