ID   ADET2_ACIBA             Reviewed;         238 AA.
AC   C7F8K7;
DT   05-DEC-2018, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 14.
DE   RecName: Full=Probable solute-binding protein AdeT2 {ECO:0000305};
GN   Name=adeT2 {ECO:0000303|PubMed:21212056};
OS   Acinetobacter baumannii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX   NCBI_TaxID=470;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=AC0037;
RX   PubMed=21212056; DOI=10.1093/jac/dkq469;
RA   Srinivasan V.B., Rajamohan G., Pancholi P., Marcon M., Gebreyes W.A.;
RT   "Molecular cloning and functional characterization of two novel membrane
RT   fusion proteins in conferring antimicrobial resistance in Acinetobacter
RT   baumannii.";
RL   J. Antimicrob. Chemother. 66:499-504(2011).
CC   -!- FUNCTION: Mediates antimicrobial resistance via active efflux.
CC       Contributes to resistance to antibiotics such as chloramphenicol,
CC       erythromycin and novobiocin (PubMed:21212056). May be part of a
CC       tripartite ATP-independent periplasmic (TRAP) transport system
CC       (Probable). {ECO:0000269|PubMed:21212056, ECO:0000305|PubMed:21212056}.
CC   -!- DISRUPTION PHENOTYPE: Deletion of the gene results in increased
CC       susceptibility to different antibiotics, dyes, detergents and
CC       disinfectants. {ECO:0000269|PubMed:21212056}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 7 family.
CC       {ECO:0000305}.
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DR   EMBL; GQ338838; ACU27399.1; -; Genomic_DNA.
DR   AlphaFoldDB; C7F8K7; -.
DR   SMR; C7F8K7; -.
DR   STRING; 470.IX87_12195; -.
DR   OMA; DQVWCAY; -.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.190.170; -; 1.
DR   InterPro; IPR045758; AdeT1/2.
DR   InterPro; IPR038404; TRAP_DctP_sf.
DR   Pfam; PF19582; DUF6091; 1.
PE   3: Inferred from homology;
KW   Antibiotic resistance; Transport.
FT   CHAIN           1..238
FT                   /note="Probable solute-binding protein AdeT2"
FT                   /id="PRO_0000445959"
SQ   SEQUENCE   238 AA;  27284 MW;  7974826242D6DADD CRC64;
     MGSTSGIGLI PNNRTARNLL QLLNHPTIEK RLINKDYEAV GMIPVGTANM VMKTKKISKV
     AQLRGQRIGV LANNPPQQAL VRSVGAQPVY VDLSNAIAQF QQNKIDIMPA PVYGLLPYNL
     QKDFGPDTQV INFPLAYFGV NIIIKPQAYP ANFGRKIRAW FVQNSQLLTN RAIQWENHLP
     AYYWVDVSFY EKQSYDIMVA KIRNQYVRSG YYDAYFVELM KRLRCIDDPR YFECPMSR