ID   DPY20_CAEEL             Reviewed;         440 AA.
AC   P34807;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 3.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Protein dumpy-20;
GN   Name=dpy-20; ORFNames=T22B3.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-349, FUNCTION, AND DEVELOPMENTAL
RP   STAGE.
RX   PubMed=7770042; DOI=10.1007/bf00293205;
RA   Clark D.V., Suleman D.S., Beckenbach K.A., Gilchrist E.J., Baillie D.L.;
RT   "Molecular cloning and characterization of the dpy-20 gene of
RT   Caenorhabditis elegans.";
RL   Mol. Gen. Genet. 247:367-378(1995).
CC   -!- FUNCTION: May be directly or indirectly involved in cuticle function.
CC       {ECO:0000269|PubMed:7770042}.
CC   -!- DEVELOPMENTAL STAGE: Expressed predominantly in the second larval
CC       stage. {ECO:0000269|PubMed:7770042}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA85278.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; Z68300; CAA92616.2; -; Genomic_DNA.
DR   EMBL; U01918; AAA85278.1; ALT_SEQ; Genomic_DNA.
DR   PIR; T25097; T25097.
DR   RefSeq; NP_502215.2; NM_069814.4.
DR   AlphaFoldDB; P34807; -.
DR   STRING; 6239.T22B3.1; -.
DR   PaxDb; P34807; -.
DR   EnsemblMetazoa; T22B3.1.1; T22B3.1.1; WBGene00001079.
DR   GeneID; 178105; -.
DR   KEGG; cel:CELE_T22B3.1; -.
DR   UCSC; T22B3.1; c. elegans.
DR   CTD; 178105; -.
DR   WormBase; T22B3.1; CE40520; WBGene00001079; dpy-20.
DR   eggNOG; ENOG502TGV1; Eukaryota.
DR   HOGENOM; CLU_681947_0_0_1; -.
DR   InParanoid; P34807; -.
DR   OMA; MNDVGIR; -.
DR   OrthoDB; 913874at2759; -.
DR   PRO; PR:P34807; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00001079; Expressed in larva.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:1990837; F:sequence-specific double-stranded DNA binding; HDA:WormBase.
DR   InterPro; IPR003656; Znf_BED.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   Pfam; PF02892; zf-BED; 2.
DR   SUPFAM; SSF57667; SSF57667; 2.
DR   PROSITE; PS50808; ZF_BED; 2.
PE   2: Evidence at transcript level;
KW   Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..440
FT                   /note="Protein dumpy-20"
FT                   /id="PRO_0000079995"
FT   ZN_FING         137..186
FT                   /note="BED-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   ZN_FING         350..399
FT                   /note="BED-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   REGION          96..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         156
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         159
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         174
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         179
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         369
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         372
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         387
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         392
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
SQ   SEQUENCE   440 AA;  49834 MW;  99CB6E4DBEA34BC8 CRC64;
     MEGHSNTSVI LHTYQQQQPQ QLISSIIPQT LSDGYGISAP ISQADCSGNS NFVNTNPWNN
     TTFQAYQTDA QFTNEISVLN YPNVYDDFSK ESSNGILSDP SLHGSNSSSS TSDVGSSVDC
     SISPEPILMP SVKRGRPTEN PCWAYFHRID DQLVKCRLCT KVVRSACATN MTKHLERHHA
     DDYQKVTGQL KLFRMNDVGI RSKMHYEVAD NPLSTLPVVT NSYILPKMEP MDTFDPSQYY
     GMQQDPTLNQ QQFIQFEQPQ ASIDPQTWPL THFWQNTAQT NIMSHLGEAS TSTLGSSVIQ
     EAHKMNPDSN DKSFQLDLEQ QNCVIIEQKL DDKPRVTKPT TKPYQKRNRK TEHPVWAFFK
     RTGDGNAECI ICQGVVKSPC SSNFMRHLMR HHSTEYNDVY LKWIEKRNIT HPGIHCTSVP
     PPAFINNETS RTEQTTFSVK