ID   DQRP_ACRMI              Reviewed;         522 AA.
AC   B7W112;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=Aspartic and glutamic acid-rich protein {ECO:0000303|PubMed:23765379};
DE   Flags: Precursor;
OS   Acropora millepora (Staghorn coral) (Heteropora millepora).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Acroporidae; Acropora.
OX   NCBI_TaxID=45264;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=22490231; DOI=10.1111/j.1365-294x.2012.05554.x;
RA   Moya A., Huisman L., Ball E.E., Hayward D.C., Grasso L.C., Chua C.M.,
RA   Woo H.N., Gattuso J.P., Foret S., Miller D.J.;
RT   "Whole transcriptome analysis of the coral Acropora millepora reveals
RT   complex responses to CO(2)-driven acidification during the initiation of
RT   calcification.";
RL   Mol. Ecol. 21:2440-2454(2012).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 287-305 AND 397-426, TISSUE SPECIFICITY, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=23765379; DOI=10.1093/molbev/mst109;
RA   Ramos-Silva P., Kaandorp J., Huisman L., Marie B., Zanella-Cleon I.,
RA   Guichard N., Miller D.J., Marin F.;
RT   "The skeletal proteome of the coral Acropora millepora: the evolution of
RT   calcification by co-option and domain shuffling.";
RL   Mol. Biol. Evol. 30:2099-2112(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:23765379}.
CC   -!- TISSUE SPECIFICITY: Component of the acid-soluble organic matrix of the
CC       aragonitic skeleton (at protein level). {ECO:0000269|PubMed:23765379}.
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DR   EMBL; JR983175; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; B7W112; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Coiled coil; Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..522
FT                   /note="Aspartic and glutamic acid-rich protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000429554"
FT   REGION          72..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          319..465
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        72..111
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..143
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..171
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..203
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..288
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..349
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        350..380
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..398
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..495
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   522 AA;  60167 MW;  1B1C0247FD444231 CRC64;
     MKVFVYLLVT FSLTNASPLR NRFNEDHDEF SKDDMARESF DTEEMYNAFL NRRDSSESQL
     EDHLLSHAKP LYDDFFPKDT SPDDDEDSYW LESRNDDGYD LAKRKRGYDD EEAYDDFDEV
     DDRADDEGAR DVDESDFEED DKLPAEEESK NDMDEETFED EPEEDKEEAR EEFAEDERAD
     EREDDDADFD FNDEEDEDEV DNKAESDIFT PEDFAGVSDE AMDNFRDDNE EEYADESDDE
     AEEDSEETAD DFEDDPEDES DETFRDEVED ESEENYQDDT EEGSEIKQND ETEEQPEKKF
     DADKEHEDAP EPLKEKLSDE SKARAEDESD KSEDAAKEIK EPEDAVEDFE DGAKVSEDEA
     ELLDDEAELS DDEAELSKDE AEQSSDEAEK SEDKAEKSED EAELSEDEAK QSEDEAEKAE
     DAAGKESNDE GKKREDEAVK SKGIARDESE FAKAKKSNLA LKRDENRPLA KGLRESAAHL
     RDFPSEKKSK DAAQGNIENE LDYFKRNAFA DSKDAEPYEF DK