ID   DR774_DEIRA             Reviewed;         740 AA.
AC   Q9RW95;
DT   26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Probable type IV piliation system protein DR_0774 {ECO:0000305};
DE   Flags: Precursor;
GN   OrderedLocusNames=DR_0774 {ECO:0000312|EMBL:AAF10350.1};
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION, AND SUBCELLULAR LOCATION.
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=24589688; DOI=10.1016/j.bbamem.2014.02.014;
RA   Farci D., Bowler M.W., Kirkpatrick J., McSweeney S., Tramontano E.,
RA   Piano D.;
RT   "New features of the cell wall of the radio-resistant bacterium Deinococcus
RT   radiodurans.";
RL   Biochim. Biophys. Acta 1838:1978-1984(2014).
CC   -!- FUNCTION: Could be part of the type IV piliation system (T4P). May
CC       contribute at the cohesion between the S-layer and the outer membrane
CC       by forming oligomers. Could also be the main channel through which
CC       trafficking is managed. {ECO:0000303|PubMed:24589688}.
CC   -!- SUBCELLULAR LOCATION: Cell envelope {ECO:0000269|PubMed:24589688}.
CC   -!- SIMILARITY: Belongs to the bacterial secretin family. {ECO:0000305}.
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DR   EMBL; AE000513; AAF10350.1; -; Genomic_DNA.
DR   PIR; G75477; G75477.
DR   RefSeq; NP_294498.1; NC_001263.1.
DR   RefSeq; WP_010887420.1; NZ_CP015081.1.
DR   AlphaFoldDB; Q9RW95; -.
DR   STRING; 243230.DR_0774; -.
DR   EnsemblBacteria; AAF10350; AAF10350; DR_0774.
DR   KEGG; dra:DR_0774; -.
DR   PATRIC; fig|243230.17.peg.954; -.
DR   eggNOG; COG1450; Bacteria.
DR   HOGENOM; CLU_398870_0_0_0; -.
DR   InParanoid; Q9RW95; -.
DR   OMA; QVKLFFG; -.
DR   OrthoDB; 870677at2; -.
DR   Proteomes; UP000002524; Chromosome I.
DR   GO; GO:0031975; C:envelope; IEA:UniProtKB-SubCell.
DR   GO; GO:0015627; C:type II protein secretion system complex; IBA:GO_Central.
DR   GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR   Gene3D; 3.30.1370.120; -; 1.
DR   InterPro; IPR005644; NolW-like.
DR   InterPro; IPR038591; NolW-like_sf.
DR   InterPro; IPR004846; T2SS/T3SS.
DR   Pfam; PF00263; Secretin; 1.
DR   Pfam; PF03958; Secretin_N; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..740
FT                   /note="Probable type IV piliation system protein DR_0774"
FT                   /id="PRO_0000431097"
SQ   SEQUENCE   740 AA;  78594 MW;  CF9B37AC429E9C0E CRC64;
     MNKRHALLLT AVLGMATAYA QTAPTTTTVN TLQTVYRDPS LTSAPITANV GKYVGPLSTF
     LASIAKSAGY EVVFNFNIDA LALINGEIVF GNSTASVTTS YATPLGRPQE LPAKPVVHNF
     SNAPFNEAWP LLMDVYELDY QLVKVGSANV IRIGQRPKQL ALPLKFISAE SALTAIEKFF
     GEEKFETVIS LDSNNKPFQT TRPTGKFGLP NSIKVIPDSS NKRLIIGSNS EDGIRIRSFV
     ETIDVQSSGK VISTDSISEI YIVRGQKESV LQFLRDSFPE LIVTDYASGG LAIEGPRTSV
     NRAIILLGQV DRAPEIPIVQ RIYTVRGQAA DITALLAAQY PTLRVTPVGQ TGQLVLNGAQ
     AQLDTALALL EQVDRPAPVA ESRTVQRVFQ LVNASAEEVK ATLEGTLARD LTADSNNDVL
     PNVPVTATDA NGNTTVVSVP NALGKTANQG TANAQAQTAQ TPANTQQATL IADKRTNSLI
     VRGTPEQVAQ VAELVPQLDQ VVPQINVQVR IQEVNERALQ SLGLNWRATF GGFNVAVSGG
     TGLAATFNPT QSFLGFNIFP TLTALETQGL TRRVYDGNVT MQSGQRSLSA TGGAQNASSG
     AAASVKSGGR LEINIPSAAG NIVRQIDYGL NLDFFSPQVA PDGTITLRIR GQVNQPATAI
     TADSLPNLID FTNSEAQSTI TFKNGQTILM SGLLGSTETT NRSGVPFLSS LPGVGAAFGE
     KRTEKTQSQL LVIITGTVVK