DRB1_ORYSJ
ID DRB1_ORYSJ Reviewed; 441 AA.
AC Q5N8Z0; A0A0P0V8T1;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Double-stranded RNA-binding protein 1;
DE AltName: Full=dsRNA-binding protein 1;
GN Name=DRB1; OrderedLocusNames=Os01g0772000, LOC_Os01g56520;
GN ORFNames=P0695H10.10;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Binds double-stranded RNA. {ECO:0000250}.
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DR EMBL; AP003295; BAD82066.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS74562.1; -; Genomic_DNA.
DR EMBL; AK069455; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015639013.1; XM_015783527.1.
DR AlphaFoldDB; Q5N8Z0; -.
DR SMR; Q5N8Z0; -.
DR STRING; 4530.OS01T0772000-01; -.
DR PaxDb; Q5N8Z0; -.
DR PRIDE; Q5N8Z0; -.
DR EnsemblPlants; Os01t0772000-01; Os01t0772000-01; Os01g0772000.
DR GeneID; 4324620; -.
DR Gramene; Os01t0772000-01; Os01t0772000-01; Os01g0772000.
DR KEGG; osa:4324620; -.
DR eggNOG; ENOG502QTBA; Eukaryota.
DR HOGENOM; CLU_029158_1_0_1; -.
DR InParanoid; Q5N8Z0; -.
DR OMA; QVYPRRP; -.
DR OrthoDB; 1311940at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q5N8Z0; OS.
DR GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR CDD; cd19907; DSRM_AtDRB-like_rpt1; 1.
DR InterPro; IPR044450; AtDRB-like_DSRM_1.
DR InterPro; IPR014720; dsRBD_dom.
DR Pfam; PF00035; dsrm; 3.
DR SMART; SM00358; DSRM; 3.
DR PROSITE; PS50137; DS_RBD; 3.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..441
FT /note="Double-stranded RNA-binding protein 1"
FT /id="PRO_0000404678"
FT DOMAIN 1..71
FT /note="DRBM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT DOMAIN 86..155
FT /note="DRBM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT DOMAIN 169..237
FT /note="DRBM 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT REGION 69..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 162
FT /note="Q -> R (in Ref. 4; AK069455)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 441 AA; 47056 MW; D5F5EFC1576A811D CRC64;
MYKSRLQELC QQRRWAPPEY THRCAGPAHA PLFGATVSVN GVEFRTPEDA ARSAKEAHNI
AAKAAFDHLS SLPLPPPPPP SENQSSYKSQ LQIYAQKKGK LLPSYQTIRE GPGHASRFKS
VVTVDGKAFE SPEYFHTVKE AESAAAKLAL MSLPQEASSS EQVPVQPLSY KNLLQELAQK
HGFSLPVYST TSDGSVQVPM FKSTVVFQDG SFQGEPANTK KQAEMNAARV AFQHFEDRRK
NALSSTVLRG PHLGQGTVHI SAGQVKIAEP VFSVPLASTA TSHSATGATD RDYHSLGSTN
PLPIAKSTNC ADVHIQPCEF KDEKPAFPEP KTVLEVMDSS PELTPLEDAY SAPVASTSTV
SSSGCGSDPL ASASTVNSTG CGSVPLASAS TVSSTGCGCS LLTNRVQVYP RRPDLVLPEG
ATVLPFSDDV WVAVSLPTLN H