DRB2_ORYSJ
ID DRB2_ORYSJ Reviewed; 593 AA.
AC Q0DKP4; Q5WN06;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Double-stranded RNA-binding protein 2;
DE AltName: Full=dsRNA-binding protein 2;
DE AltName: Full=dsRNA-binding protein 3;
DE Short=OsDRB3;
GN Name=DRB2; Synonyms=DRB3; OrderedLocusNames=Os05g0150400, LOC_Os05g05790;
GN ORFNames=P0001A07.3;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Binds double-stranded RNA. {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAV32195.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AK110983; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC084218; AAV32195.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008211; BAF16579.1; -; Genomic_DNA.
DR EMBL; AP014961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK110983; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015639382.1; XM_015783896.1.
DR RefSeq; XP_015639383.1; XM_015783897.1.
DR RefSeq; XP_015639384.1; XM_015783898.1.
DR AlphaFoldDB; Q0DKP4; -.
DR SMR; Q0DKP4; -.
DR STRING; 4530.OS05T0150400-01; -.
DR PaxDb; Q0DKP4; -.
DR PRIDE; Q0DKP4; -.
DR GeneID; 4337826; -.
DR KEGG; osa:4337826; -.
DR eggNOG; ENOG502QTBA; Eukaryota.
DR HOGENOM; CLU_017946_1_0_1; -.
DR InParanoid; Q0DKP4; -.
DR OrthoDB; 1156085at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR Genevisible; Q0DKP4; OS.
DR GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR CDD; cd19907; DSRM_AtDRB-like_rpt1; 1.
DR CDD; cd19908; DSRM_AtDRB-like_rpt2; 1.
DR InterPro; IPR044450; AtDRB-like_DSRM_1.
DR InterPro; IPR044451; AtDRB-like_DSRM_2.
DR InterPro; IPR014720; dsRBD_dom.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR PROSITE; PS50137; DS_RBD; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..593
FT /note="Double-stranded RNA-binding protein 2"
FT /id="PRO_0000404679"
FT DOMAIN 1..70
FT /note="DRBM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT DOMAIN 87..155
FT /note="DRBM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT REGION 188..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 64790 MW; A77C724DBEDD109E CRC64;
MYKNQLQELA QRSCFNLPSY ACIREGPDHA PRFKATVNFN GETFESPAFC STLRLAEHAA
AEVALNELSK RGPSSSLAAK VLDETGIYKN LLQETAHRAG LKLPVYTTIR SGPGHTPVFT
CTVELAGMTF TGNPGKTKKQ AQKNAAMAAW SELKQLPRVG EPSSSSCPPD HDDDDQEQII
VARTLASLNQ TNGGKTPQQK EKQQSSNRPS SRRPSYPKSN ASFYGRLHLQ KHAYPSVPPE
QAMYHMWHQV QATQQKPHFP MVPTMGSTGF PPPPTVLHMY PPPRGQFTMP SSQDGLGLIP
CYPEASPVLP RYFSPYPASF VPRRPLPVNV HKIHEKRLVG ADMVELPDAA VFSRYTAPDF
SGTSENAVQD NKKEEYTESS PASEQESKSH TASSSATRSP SQQLESNQDI EIMGGLRLES
KKPAEQPPES SPSRVNPVLL CETGQRHHYS SVRHGDPVHR NSPQISVATS PSPIRRGDPA
HINIPQISVA TPPECRSPRA QAPPRFGTRM PVNLPSSLYQ QRPPWLAASV TIRTTIPVCS
ARPNVVNSSA GAAQPAVQIL SASPRKEEPE ARTNTSDTSN AATASSELNK LHI