DRB5_ORYSJ
ID DRB5_ORYSJ Reviewed; 404 AA.
AC B7E321; A0A0P0XPP7; B7E2T6; Q0J0H8; Q766V3;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Double-stranded RNA-binding protein 5;
DE AltName: Full=dsRNA-binding protein 2;
DE Short=OsDRB2;
DE AltName: Full=dsRNA-binding protein 5;
GN Name=DRB5; Synonyms=DRB2; OrderedLocusNames=Os09g0508500, LOC_Os09g33460;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=15821876; DOI=10.1007/s11103-004-6853-5;
RA Hiraguri A., Itoh R., Kondo N., Nomura Y., Aizawa D., Murai Y., Koiwa H.,
RA Seki M., Shinozaki K., Fukuhara T.;
RT "Specific interactions between Dicer-like proteins and HYL1/DRB-family
RT dsRNA-binding proteins in Arabidopsis thaliana.";
RL Plant Mol. Biol. 57:173-188(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Binds double-stranded RNA. {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=B7E321-1; Sequence=Displayed;
CC Name=2;
CC IsoId=B7E321-2; Sequence=VSP_040618, VSP_040619;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD07039.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC Sequence=BAF25537.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB114419; BAD07039.1; ALT_SEQ; mRNA.
DR EMBL; AP008215; BAF25537.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014965; BAT08885.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT08886.1; -; Genomic_DNA.
DR EMBL; AK058408; BAG86683.1; -; mRNA.
DR EMBL; AK058662; BAG86768.1; -; mRNA.
DR RefSeq; XP_015610736.1; XM_015755250.1. [B7E321-1]
DR RefSeq; XP_015610737.1; XM_015755251.1. [B7E321-2]
DR AlphaFoldDB; B7E321; -.
DR SMR; B7E321; -.
DR STRING; 4530.OS09T0508500-02; -.
DR PaxDb; B7E321; -.
DR PRIDE; B7E321; -.
DR EnsemblPlants; Os09t0508500-01; Os09t0508500-01; Os09g0508500. [B7E321-2]
DR EnsemblPlants; Os09t0508500-02; Os09t0508500-02; Os09g0508500. [B7E321-1]
DR GeneID; 4347527; -.
DR Gramene; Os09t0508500-01; Os09t0508500-01; Os09g0508500. [B7E321-2]
DR Gramene; Os09t0508500-02; Os09t0508500-02; Os09g0508500. [B7E321-1]
DR KEGG; osa:4347527; -.
DR eggNOG; ENOG502QTBA; Eukaryota.
DR HOGENOM; CLU_038996_0_0_1; -.
DR OMA; LVWIVCH; -.
DR OrthoDB; 1031431at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; B7E321; OS.
DR GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR CDD; cd19907; DSRM_AtDRB-like_rpt1; 1.
DR CDD; cd19908; DSRM_AtDRB-like_rpt2; 1.
DR InterPro; IPR044450; AtDRB-like_DSRM_1.
DR InterPro; IPR044451; AtDRB-like_DSRM_2.
DR InterPro; IPR014720; dsRBD_dom.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR PROSITE; PS50137; DS_RBD; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..404
FT /note="Double-stranded RNA-binding protein 5"
FT /id="PRO_0000404682"
FT DOMAIN 1..70
FT /note="DRBM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT DOMAIN 87..155
FT /note="DRBM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT REGION 195..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 156..357
FT /note="SNIRTTVSPLVFDLVWIVCHGGDVFVVVWCSAGGAQGARRRRRRGAGACGRR
FT QGARRAEAAGRLRRRRWRREGGGGVSTEEASRRRVLFVRHVAVQTSMGASVAAAAGGRT
FT QDTASPAPAAAAASGGVRLPSRRRRAGARAEEGRRAGAHAARRHAARQGGRRNAAADAV
FT LLRAVLPPRRRRRPDEALRRRRRVPRAAGGER -> MPEARKEPGGGGGEEQEHVVVAR
FT VLAALKPRDDCGGGGGEGKAAAASLPKKHLAGASCSSATSLYRHQWGRPSPPPPAAGPK
FT ILPPLHLLQQQQAAASGSRAAAAELEQERRKAAELVHMLHAVMLRDRAADAMPPPMPCY
FT YAPYYHHGGGVAPTRPFAGAAGFHAPPAVSVRSVIPVCAAPPSPRPPPRKEDDPATSSK
FT RA (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764,
FT ECO:0000303|PubMed:15821876"
FT /id="VSP_040618"
FT VAR_SEQ 358..404
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764,
FT ECO:0000303|PubMed:15821876"
FT /id="VSP_040619"
SQ SEQUENCE 404 AA; 43140 MW; C7E86B1313831485 CRC64;
MYKNQLQELA QRSCFSLPSY VCTREGPDHA PRFKATVTFN GETFDGPSNC TTLRQAEHAA
AEVALARLSL RGPSSSLTAR VLDETGVYKN LLQETAHRAG LKLPVYTTVR SGPGHSPVFS
STVELAGMSF AGDPAKTKKH AEKNAAMAAW SSLKQSNIRT TVSPLVFDLV WIVCHGGDVF
VVVWCSAGGA QGARRRRRRG AGACGRRQGA RRAEAAGRLR RRRWRREGGG GVSTEEASRR
RVLFVRHVAV QTSMGASVAA AAGGRTQDTA SPAPAAAAAS GGVRLPSRRR RAGARAEEGR
RAGAHAARRH AARQGGRRNA AADAVLLRAV LPPRRRRRPD EALRRRRRVP RAAGGERPFS
DPGLRRATVA AAAAAQGGRS SDLIQEGVVV VKTSIQSIAQ PAPI
