DRB8_ORYSJ
ID DRB8_ORYSJ Reviewed; 424 AA.
AC Q0IQN6; H2KX80; Q4ZH87; Q9LRF5;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Double-stranded RNA-binding protein 8;
DE AltName: Full=dsRNA-binding protein 1;
DE Short=OsDRB1;
DE AltName: Full=dsRNA-binding protein 8;
GN Name=DRB8; Synonyms=DRB1; OrderedLocusNames=Os12g0109900, LOC_Os12g01916;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RC STRAIN=cv. Nipponbare;
RX PubMed=15821876; DOI=10.1007/s11103-004-6853-5;
RA Hiraguri A., Itoh R., Kondo N., Nomura Y., Aizawa D., Murai Y., Koiwa H.,
RA Seki M., Shinozaki K., Fukuhara T.;
RT "Specific interactions between Dicer-like proteins and HYL1/DRB-family
RT dsRNA-binding proteins in Arabidopsis thaliana.";
RL Plant Mol. Biol. 57:173-188(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-410.
RC TISSUE=Leaf;
RA Tang X., Wu H., Jia M., Yu X., He Y.;
RT "Isolation and expressional analysis of cDNA encoding a dsRNA binding
RT protein homolog OsRBP of rice.";
RL Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao 28:41-45(2002).
CC -!- FUNCTION: Binds double-stranded RNA. {ECO:0000269|PubMed:15821876}.
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DR EMBL; AB036988; BAB00641.1; -; mRNA.
DR EMBL; DP000011; ABG21849.1; -; Genomic_DNA.
DR EMBL; AP008218; BAF28979.1; -; Genomic_DNA.
DR EMBL; AP014968; BAT15545.1; -; Genomic_DNA.
DR EMBL; DQ009988; AAY21792.1; -; mRNA.
DR RefSeq; XP_015620826.1; XM_015765340.1.
DR AlphaFoldDB; Q0IQN6; -.
DR SMR; Q0IQN6; -.
DR STRING; 39947.Q0IQN6; -.
DR PaxDb; Q0IQN6; -.
DR PRIDE; Q0IQN6; -.
DR EnsemblPlants; Os12t0109900-01; Os12t0109900-01; Os12g0109900.
DR GeneID; 4351288; -.
DR Gramene; Os12t0109900-01; Os12t0109900-01; Os12g0109900.
DR KEGG; osa:4351288; -.
DR HOGENOM; CLU_034148_0_0_1; -.
DR InParanoid; Q0IQN6; -.
DR OrthoDB; 1344243at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR ExpressionAtlas; Q0IQN6; baseline and differential.
DR Genevisible; Q0IQN6; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR GO; GO:0004525; F:ribonuclease III activity; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR GO; GO:0006396; P:RNA processing; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR011907; RNase_III.
DR PANTHER; PTHR11207; PTHR11207; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR PROSITE; PS50137; DS_RBD; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..424
FT /note="Double-stranded RNA-binding protein 8"
FT /id="PRO_0000404685"
FT DOMAIN 33..102
FT /note="DRBM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT DOMAIN 118..185
FT /note="DRBM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 8
FT /note="L -> R (in Ref. 6; AAY21792)"
FT /evidence="ECO:0000305"
FT CONFLICT 156..159
FT /note="GGIQ -> WWEYK (in Ref. 1; BAB00641)"
FT /evidence="ECO:0000305"
FT CONFLICT 309
FT /note="S -> C (in Ref. 1; BAB00641)"
FT /evidence="ECO:0000305"
FT CONFLICT 334
FT /note="Q -> H (in Ref. 6; AAY21792 and 1; BAB00641)"
FT /evidence="ECO:0000305"
FT CONFLICT 410
FT /note="I -> M (in Ref. 6; AAY21792)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 424 AA; 46113 MW; 151E5743C3565A2C CRC64;
MDMPPTPLPP ETANTSPAPN GATAGIRVEN CYVFKSRLQE YAQKTGLQTP EYHTFKEGPS
HEPVFKSTVV INNTSYDSLP GFFNRKAAEQ SAAEVALMEI VKSIPANANI PAVQETGLCK
NLLQEYAQKM NYAIPSYICT KSASGLAPFI CTVEIGGIQY IGAAARTKKD AEIKAARTAL
LAIQGQSEGS ANGATKYIVV PGKRVGKEVE KRPIETPKPL KVKKGGFKKK WNKRKFMKKD
GQAVDVEKDE ARVAGDAHDS DVLMQPTVIT QEASCGTLFL QPCEEAKRVE AEPPRDIEMV
QPDKENQHSD AALVQPDDEA RVEQEPSRDI SVVQPNEEAI SGKQEPSIDA AILQPKEEAS
SVKQEPFIDT AMLQACKEAG SVELGPARDT VISQLNEQDR AVKQEPAGDI VVPQPDVHAR
VVKE
