DRE1D_ARATH
ID DRE1D_ARATH Reviewed; 224 AA.
AC Q9FJ93; A0MFN5; Q1PDK4; Q6J9R8;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Dehydration-responsive element-binding protein 1D;
DE Short=Protein DREB1D;
DE AltName: Full=C-repeat/dehydration-responsive element-binding factor 4;
DE Short=C-repeat-binding factor 4;
DE Short=CRT/DRE-binding factor 4;
GN Name=DREB1D; Synonyms=CBF4, ERF028; OrderedLocusNames=At5g51990;
GN ORFNames=MSG15.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9872454; DOI=10.1093/dnares/5.5.297;
RA Nakamura Y., Sato S., Asamizu E., Kaneko T., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence
RT features of the regions of 1,013,767 bp covered by sixteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:297-308(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP GENE FAMILY, FUNCTION, AND INDUCTION.
RX PubMed=11798174; DOI=10.1006/bbrc.2001.6299;
RA Sakuma Y., Liu Q., Dubouzet J.G., Abe H., Shinozaki K.,
RA Yamaguchi-Shinozaki K.;
RT "DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs,
RT transcription factors involved in dehydration- and cold-inducible gene
RT expression.";
RL Biochem. Biophys. Res. Commun. 290:998-1009(2002).
RN [6]
RP FUNCTION, AND INDUCTION.
RX PubMed=12376631; DOI=10.1104/pp.006478;
RA Haake V., Cook D., Riechmann J.L., Pineda O., Thomashow M.F., Zhang J.Z.;
RT "Transcription factor CBF4 is a regulator of drought adaptation in
RT Arabidopsis.";
RL Plant Physiol. 130:639-648(2002).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates
CC abscisic acid- and dehydration-inducible transcription. CBF/DREB1
CC factors play a key role in freezing tolerance and cold acclimation.
CC {ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:12376631}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- INDUCTION: By high-salt stress, drought stress and abscisic acid (ABA)
CC treatment. {ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:12376631}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28752.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AY560857; AAT44924.1; -; mRNA.
DR EMBL; AB015478; BAB11047.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96156.1; -; Genomic_DNA.
DR EMBL; DQ447064; ABE66241.1; -; mRNA.
DR EMBL; DQ653361; ABK28752.1; ALT_SEQ; mRNA.
DR RefSeq; NP_200012.1; NM_124578.2.
DR AlphaFoldDB; Q9FJ93; -.
DR BioGRID; 20519; 3.
DR STRING; 3702.AT5G51990.1; -.
DR PaxDb; Q9FJ93; -.
DR PRIDE; Q9FJ93; -.
DR EnsemblPlants; AT5G51990.1; AT5G51990.1; AT5G51990.
DR GeneID; 835274; -.
DR Gramene; AT5G51990.1; AT5G51990.1; AT5G51990.
DR KEGG; ath:AT5G51990; -.
DR Araport; AT5G51990; -.
DR TAIR; locus:2173113; AT5G51990.
DR eggNOG; ENOG502QQ5M; Eukaryota.
DR HOGENOM; CLU_063331_1_0_1; -.
DR OMA; FFENMAE; -.
DR OrthoDB; 1352198at2759; -.
DR PhylomeDB; Q9FJ93; -.
DR PRO; PR:Q9FJ93; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FJ93; baseline and differential.
DR Genevisible; Q9FJ93; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0019760; P:glucosinolate metabolic process; IMP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR045277; DRE1A-I.
DR PANTHER; PTHR31839; PTHR31839; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Abscisic acid signaling pathway; Activator; DNA-binding; Nucleus;
KW Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..224
FT /note="Dehydration-responsive element-binding protein 1D"
FT /id="PRO_0000112531"
FT DNA_BIND 53..110
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 20..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 38..50
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 155..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 224 AA; 24956 MW; 606C97EA4E4AF52F CRC64;
MNPFYSTFPD SFLSISDHRS PVSDSSECSP KLASSCPKKR AGRKKFRETR HPIYRGVRQR
NSGKWVCEVR EPNKKSRIWL GTFPTVEMAA RAHDVAALAL RGRSACLNFA DSAWRLRIPE
TTCPKEIQKA ASEAAMAFQN ETTTEGSKTA AEAEEAAGEG VREGERRAEE QNGGVFYMDD
EALLGMPNFF ENMAEGMLLP PPEVGWNHND FDGVGDVSLW SFDE
