DRE1E_ARATH
ID DRE1E_ARATH Reviewed; 181 AA.
AC Q9SGJ6; Q1ECJ2; Q680B6; Q6J9T4;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Dehydration-responsive element-binding protein 1E;
DE Short=Protein DREB1E;
GN Name=DREB1E; Synonyms=DDF1, ERF032; OrderedLocusNames=At1g63030;
GN ORFNames=F16M19.20, F16P17.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND FUNCTION.
RX PubMed=11798174; DOI=10.1006/bbrc.2001.6299;
RA Sakuma Y., Liu Q., Dubouzet J.G., Abe H., Shinozaki K.,
RA Yamaguchi-Shinozaki K.;
RT "DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs,
RT transcription factors involved in dehydration- and cold-inducible gene
RT expression.";
RL Biochem. Biophys. Res. Commun. 290:998-1009(2002).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates
CC cold or dehydration-inducible transcription. CBF/DREB1 factors play a
CC key role in freezing tolerance and cold acclimation.
CC {ECO:0000269|PubMed:11798174}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AY560841; AAT44908.1; -; mRNA.
DR EMBL; AC010795; AAG51606.1; -; Genomic_DNA.
DR EMBL; AC011000; AAF75816.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34043.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34044.1; -; Genomic_DNA.
DR EMBL; AK175951; BAD43714.1; -; mRNA.
DR EMBL; BT021917; AAX49366.1; -; mRNA.
DR EMBL; BT025742; ABF83632.1; -; mRNA.
DR PIR; E96655; E96655.
DR RefSeq; NP_001077764.1; NM_001084295.2.
DR RefSeq; NP_176491.1; NM_104981.4.
DR AlphaFoldDB; Q9SGJ6; -.
DR STRING; 3702.AT1G63030.2; -.
DR PaxDb; Q9SGJ6; -.
DR PRIDE; Q9SGJ6; -.
DR EnsemblPlants; AT1G63030.1; AT1G63030.1; AT1G63030.
DR EnsemblPlants; AT1G63030.2; AT1G63030.2; AT1G63030.
DR GeneID; 842606; -.
DR Gramene; AT1G63030.1; AT1G63030.1; AT1G63030.
DR Gramene; AT1G63030.2; AT1G63030.2; AT1G63030.
DR KEGG; ath:AT1G63030; -.
DR Araport; AT1G63030; -.
DR TAIR; locus:2015168; AT1G63030.
DR eggNOG; ENOG502RY2A; Eukaryota.
DR HOGENOM; CLU_063331_1_0_1; -.
DR InParanoid; Q9SGJ6; -.
DR OMA; YEDLSLW; -.
DR OrthoDB; 1352198at2759; -.
DR PhylomeDB; Q9SGJ6; -.
DR PRO; PR:Q9SGJ6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SGJ6; baseline and differential.
DR Genevisible; Q9SGJ6; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0010371; P:regulation of gibberellin biosynthetic process; IMP:TAIR.
DR GO; GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IMP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR045277; DRE1A-I.
DR PANTHER; PTHR31839; PTHR31839; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..181
FT /note="Dehydration-responsive element-binding protein 1E"
FT /id="PRO_0000112532"
FT DNA_BIND 29..86
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT MOTIF 14..26
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT CONFLICT 57
FT /note="G -> R (in Ref. 4; BAD43714)"
FT /evidence="ECO:0000305"
FT CONFLICT 130
FT /note="S -> G (in Ref. 4; BAD43714)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 181 AA; 20649 MW; 97410AD3FB984D99 CRC64;
MENDDITVAE MKPKKRAGRR IFKETRHPIY RGVRRRDGDK WVCEVREPIH QRRVWLGTYP
TADMAARAHD VAVLALRGRS ACLNFSDSAW RLPVPASTDP DTIRRTAAEA AEMFRPPEFS
TGITVLPSAS EFDTSDEGVA GMMMRLAEEP LMSPPRSYID MNTSVYVDEE MCYEDLSLWS
Y
