DRE2A_ORYSJ
ID DRE2A_ORYSJ Reviewed; 274 AA.
AC Q0JQF7; A0A0N7KCE1; A2ZPM2; Q8LLU9;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Dehydration-responsive element-binding protein 2A;
DE Short=OsDREB2A;
GN Name=DREB2A; Synonyms=ERF40;
GN OrderedLocusNames=Os01g0165000, LOC_Os01g07120; ORFNames=OsJ_000494;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INDUCTION, AND GENE FAMILY.
RX PubMed=12609047; DOI=10.1046/j.1365-313x.2003.01661.x;
RA Dubouzet J.G., Sakuma Y., Ito Y., Kasuga M., Dubouzet E.G., Miura S.,
RA Seki M., Shinozaki K., Yamaguchi-Shinozaki K.;
RT "OsDREB genes in rice, Oryza sativa L., encode transcription activators
RT that function in drought-, high-salt- and cold-responsive gene
RT expression.";
RL Plant J. 33:751-763(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY.
RC STRAIN=cv. Nipponbare;
RX PubMed=16244905; DOI=10.1007/s11103-005-2498-2;
RA Skinner J.S., von Zitzewitz J., Szuecs P., Marquez-Cedillo L.,
RA Filichkin T., Amundsen K., Stockinger E.J., Thomashow M.F., Chen T.H.H.,
RA Hayes P.M.;
RT "Structural, functional, and phylogenetic characterization of a large CBF
RT gene family in barley.";
RL Plant Mol. Biol. 59:533-551(2005).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [9]
RP SUBCELLULAR LOCATION.
RX PubMed=20049613; DOI=10.1007/s00438-009-0506-y;
RA Matsukura S., Mizoi J., Yoshida T., Todaka D., Ito Y., Maruyama K.,
RA Shinozaki K., Yamaguchi-Shinozaki K.;
RT "Comprehensive analysis of rice DREB2-type genes that encode transcription
RT factors involved in the expression of abiotic stress-responsive genes.";
RL Mol. Genet. Genomics 283:185-196(2010).
CC -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive
CC element (DRE). Binding to the C-repeat/DRE element mediates high
CC salinity- and dehydration-inducible transcription.
CC {ECO:0000269|PubMed:12609047}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366,
CC ECO:0000269|PubMed:20049613}.
CC -!- INDUCTION: By high-salt and drought stresses.
CC {ECO:0000269|PubMed:12609047}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAZ10669.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF300971; AAN02487.2; -; mRNA.
DR EMBL; AP008207; BAF04021.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS70561.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ10669.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK121956; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015621339.1; XM_015765853.1.
DR AlphaFoldDB; Q0JQF7; -.
DR SMR; Q0JQF7; -.
DR STRING; 4530.OS01T0165000-02; -.
DR PaxDb; Q0JQF7; -.
DR PRIDE; Q0JQF7; -.
DR EnsemblPlants; Os01t0165000-01; Os01t0165000-01; Os01g0165000.
DR EnsemblPlants; Os01t0165000-02; Os01t0165000-02; Os01g0165000.
DR Gramene; Os01t0165000-01; Os01t0165000-01; Os01g0165000.
DR Gramene; Os01t0165000-02; Os01t0165000-02; Os01g0165000.
DR KEGG; osa:4324418; -.
DR eggNOG; ENOG502QTBU; Eukaryota.
DR HOGENOM; CLU_046486_2_0_1; -.
DR InParanoid; Q0JQF7; -.
DR OMA; HEEYQDG; -.
DR OrthoDB; 1404403at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; Q0JQF7; OS.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Stress response;
KW Transcription; Transcription regulation.
FT CHAIN 1..274
FT /note="Dehydration-responsive element-binding protein 2A"
FT /id="PRO_0000323028"
FT DNA_BIND 75..132
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 81
FT /note="Q -> A (in Ref. 6; AK121956)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 274 AA; 30665 MW; E7313A6FCB531B4F CRC64;
MERGEGRRGD CSVQVRKKRT RRKSDGPDSI AETIKWWKEQ NQKLQEENSS RKAPAKGSKK
GCMAGKGGPE NSNCAYRGVR QRTWGKWVAE IREPNRGRRL WLGSFPTALE AAHAYDEAAR
AMYGPTARVN FADNSTDANS GCTSAPSLMM SNGPATIPSD EKDELESPPF IVANGPAVLY
QPDKKDVLER VVPEVQDVKT EGSNGLKRVC QERKNMEVCE SEGIVLHKEV NISYDYFNVH
EVVEMIIVEL SADQKTEVHE EYQEGDDGFS LFSY
