DRE2B_ORYSJ
ID DRE2B_ORYSJ Reviewed; 373 AA.
AC Q5W6R4; B9FP08; Q0DIZ9;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Dehydration-responsive element-binding protein 2B;
DE Short=OsDREB2B;
GN Name=DREB2B; Synonyms=ERF42;
GN OrderedLocusNames=Os05g0346200, LOC_Os05g27930;
GN ORFNames=B1036C05.12, B1164G01.2, OsJ_18158;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, INDUCTION, AND ALTERNATIVE SPLICING.
RX PubMed=20049613; DOI=10.1007/s00438-009-0506-y;
RA Matsukura S., Mizoi J., Yoshida T., Todaka D., Ito Y., Maruyama K.,
RA Shinozaki K., Yamaguchi-Shinozaki K.;
RT "Comprehensive analysis of rice DREB2-type genes that encode transcription
RT factors involved in the expression of abiotic stress-responsive genes.";
RL Mol. Genet. Genomics 283:185-196(2010).
CC -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive
CC element (DRE). Binding to the C-repeat/DRE element mediates high
CC salinity- and dehydration-inducible transcription. Involved in drought
CC and heat-shock stress tolerance. {ECO:0000269|PubMed:20049613}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366,
CC ECO:0000269|PubMed:20049613}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1; Synonyms=DREB2B2;
CC IsoId=Q5W6R4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5W6R4-2; Sequence=VSP_039704;
CC Name=3; Synonyms=DREB2B1;
CC IsoId=Q5W6R4-3; Sequence=VSP_039705, VSP_039706;
CC -!- INDUCTION: By heat shock, high-salt and drought stresses.
CC {ECO:0000269|PubMed:20049613}.
CC -!- MISCELLANEOUS: [Isoform 3]: Inactive. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AC134927; AAV43805.1; -; Genomic_DNA.
DR EMBL; AC134928; AAV43810.1; -; Genomic_DNA.
DR EMBL; AP008211; BAF17174.2; -; Genomic_DNA.
DR EMBL; AP014961; BAS93499.1; -; Genomic_DNA.
DR EMBL; CM000142; EEE63347.1; -; Genomic_DNA.
DR EMBL; AK071850; BAG92728.1; -; mRNA.
DR EMBL; AK099221; BAG94003.1; -; mRNA.
DR RefSeq; XP_015639655.1; XM_015784169.1. [Q5W6R4-1]
DR AlphaFoldDB; Q5W6R4; -.
DR SMR; Q5W6R4; -.
DR STRING; 39947.Q5W6R4; -.
DR PaxDb; Q5W6R4; -.
DR PRIDE; Q5W6R4; -.
DR EnsemblPlants; Os05t0346200-01; Os05t0346200-01; Os05g0346200. [Q5W6R4-3]
DR GeneID; 4338484; -.
DR Gramene; Os05t0346200-01; Os05t0346200-01; Os05g0346200. [Q5W6R4-3]
DR KEGG; osa:4338484; -.
DR InParanoid; Q5W6R4; -.
DR OrthoDB; 1404403at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000007752; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR GO; GO:0009408; P:response to heat; IMP:UniProtKB.
DR GO; GO:0009651; P:response to salt stress; IMP:UniProtKB.
DR GO; GO:0009414; P:response to water deprivation; IMP:UniProtKB.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW Stress response; Transcription; Transcription regulation.
FT CHAIN 1..373
FT /note="Dehydration-responsive element-binding protein 2B"
FT /id="PRO_0000397868"
FT DNA_BIND 88..145
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..75
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_039704"
FT VAR_SEQ 27..93
FT /note="KRPRRSRDGPTSVAETIKRWAELNNQQELDPQGPKKARKAPAKGSKKGCMKG
FT KGGPENTRCDFRGVR -> CGGEESTGNLDSVQPIGKSDHGDHAMDLLQLQRPSSGGPS
FT STISRSLIHRVQRRQGRHLQRVQRRAA (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_039705"
FT VAR_SEQ 94..373
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000305"
FT /id="VSP_039706"
SQ SEQUENCE 373 AA; 40473 MW; 9C8CE2CB111367CA CRC64;
MTVDQRTTAK AIMPPVEMPP VQPGRKKRPR RSRDGPTSVA ETIKRWAELN NQQELDPQGP
KKARKAPAKG SKKGCMKGKG GPENTRCDFR GVRQRTWGKW VAEIREPNQQ SRLWLGTFPT
AEAAACAYDE AARAMYGPMA RTNFGQHHAP AASVQVALAA VKCALPGGGL TASKSRTSTQ
GASADVQDVL TGGLSACEST TTTINNQSDV VSTLHKPEEV SEISSPLRAP PAVLEDGSNE
DKAESVTYDE NIVSQQRAPP EAEASNGRGE EVFEPLEPIA SLPEDQGDYC FDIDEMLRMM
EADPTNEGLW KGDKDGSDAI LELGQDEPFY YEGVDPGMLD NLLRSDEPAW LLADPAMFIS
GGFEDDSQFF EGL
