ID   DRE2D_ARATH             Reviewed;         206 AA.
AC   Q9LQZ2; Q680G5;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=Dehydration-responsive element-binding protein 2D;
DE            Short=Protein DREB2D;
GN   Name=DREB2D; Synonyms=ERF049; OrderedLocusNames=At1g75490;
GN   ORFNames=F10A5.29;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY, FUNCTION, AND INDUCTION.
RX   PubMed=11798174; DOI=10.1006/bbrc.2001.6299;
RA   Sakuma Y., Liu Q., Dubouzet J.G., Abe H., Shinozaki K.,
RA   Yamaguchi-Shinozaki K.;
RT   "DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs,
RT   transcription factors involved in dehydration- and cold-inducible gene
RT   expression.";
RL   Biochem. Biophys. Res. Commun. 290:998-1009(2002).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16407444; DOI=10.1104/pp.105.073783;
RA   Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT   "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL   Plant Physiol. 140:411-432(2006).
CC   -!- FUNCTION: Putative transcriptional activator that binds specifically to
CC       the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element
CC       mediates high salinity-inducible transcription.
CC       {ECO:0000269|PubMed:11798174}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: By high-salt stress. {ECO:0000269|PubMed:11798174}.
CC   -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AC006434; AAF87124.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE35725.1; -; Genomic_DNA.
DR   EMBL; AK175902; BAD43665.1; -; mRNA.
DR   RefSeq; NP_177681.2; NM_106202.3.
DR   AlphaFoldDB; Q9LQZ2; -.
DR   SMR; Q9LQZ2; -.
DR   BioGRID; 29104; 3.
DR   IntAct; Q9LQZ2; 1.
DR   STRING; 3702.AT1G75490.1; -.
DR   PaxDb; Q9LQZ2; -.
DR   PRIDE; Q9LQZ2; -.
DR   ProteomicsDB; 242295; -.
DR   EnsemblPlants; AT1G75490.1; AT1G75490.1; AT1G75490.
DR   GeneID; 843885; -.
DR   Gramene; AT1G75490.1; AT1G75490.1; AT1G75490.
DR   KEGG; ath:AT1G75490; -.
DR   Araport; AT1G75490; -.
DR   TAIR; locus:2005704; AT1G75490.
DR   eggNOG; ENOG502RYIB; Eukaryota.
DR   HOGENOM; CLU_046486_2_0_1; -.
DR   InParanoid; Q9LQZ2; -.
DR   OMA; VMDDSSI; -.
DR   OrthoDB; 1397829at2759; -.
DR   PhylomeDB; Q9LQZ2; -.
DR   PRO; PR:Q9LQZ2; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9LQZ2; baseline and differential.
DR   Genevisible; Q9LQZ2; AT.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd00018; AP2; 1.
DR   Gene3D; 3.30.730.10; -; 1.
DR   InterPro; IPR001471; AP2/ERF_dom.
DR   InterPro; IPR036955; AP2/ERF_dom_sf.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   Pfam; PF00847; AP2; 1.
DR   PRINTS; PR00367; ETHRSPELEMNT.
DR   SMART; SM00380; AP2; 1.
DR   SUPFAM; SSF54171; SSF54171; 1.
DR   PROSITE; PS51032; AP2_ERF; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Stress response;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..206
FT                   /note="Dehydration-responsive element-binding protein 2D"
FT                   /id="PRO_0000112537"
FT   DNA_BIND        41..98
FT                   /note="AP2/ERF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT   REGION          13..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          102..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   206 AA;  22580 MW;  FDB57867B2A22911 CRC64;
     MSSIEPKVMM VGANKKQRTV QASSRKGCMR GKGGPDNASC TYKGVRQRTW GKWVAEIREP
     NRGARLWLGT FDTSREAALA YDSAARKLYG PEAHLNLPES LRSYPKTASS PASQTTPSSN
     TGGKSSSDSE SPCSSNEMSS CGRVTEEISW EHINVDLPVM DDSSIWEEAT MSLGFPWVHE
     GDNDISRFDT CISGGYSNWD SFHSPL