DRE2E_ARATH
ID DRE2E_ARATH Reviewed; 244 AA.
AC O80917;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Dehydration-responsive element-binding protein 2E;
DE Short=Protein DREB2E;
DE AltName: Full=Dehydration response element-binding protein 19 {ECO:0000303|PubMed:21069430};
GN Name=DREB2E; Synonyms=DREB19 {ECO:0000303|PubMed:21069430}, ERF046;
GN OrderedLocusNames=At2g38340; ORFNames=T19C21.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, FUNCTION, AND INDUCTION.
RX PubMed=11798174; DOI=10.1006/bbrc.2001.6299;
RA Sakuma Y., Liu Q., Dubouzet J.G., Abe H., Shinozaki K.,
RA Yamaguchi-Shinozaki K.;
RT "DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs,
RT transcription factors involved in dehydration- and cold-inducible gene
RT expression.";
RL Biochem. Biophys. Res. Commun. 290:998-1009(2002).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=21069430; DOI=10.1007/s11103-010-9711-7;
RA Krishnaswamy S., Verma S., Rahman M.H., Kav N.N.;
RT "Functional characterization of four APETALA2-family genes (RAP2.6,
RT RAP2.6L, DREB19 and DREB26) in Arabidopsis.";
RL Plant Mol. Biol. 75:107-127(2011).
CC -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates
CC abscisic acid-inducible transcription. Involved in the regulation of
CC plant development and tolerance to abiotic stresses (PubMed:21069430).
CC {ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:21069430}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366,
CC ECO:0000269|PubMed:21069430}.
CC -!- TISSUE SPECIFICITY: Expressed in xylem tissues, stigma, anthers and
CC region where sepals and petals attach the peduncle.
CC {ECO:0000269|PubMed:21069430}.
CC -!- INDUCTION: By abscisic acid (ABA) treatment (PubMed:11798174). Induced
CC by salt, heat and drought stresses. {ECO:0000269|PubMed:11798174}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AC004683; AAC28770.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09525.1; -; Genomic_DNA.
DR EMBL; AY072421; AAL62413.1; -; mRNA.
DR EMBL; BT006276; AAP13384.1; -; mRNA.
DR PIR; T02511; T02511.
DR RefSeq; NP_001318372.1; NM_001336696.1.
DR AlphaFoldDB; O80917; -.
DR BioGRID; 3756; 4.
DR IntAct; O80917; 4.
DR STRING; 3702.AT2G38340.1; -.
DR PaxDb; O80917; -.
DR PRIDE; O80917; -.
DR ProteomicsDB; 242296; -.
DR EnsemblPlants; AT2G38340.1; AT2G38340.1; AT2G38340.
DR GeneID; 818414; -.
DR Gramene; AT2G38340.1; AT2G38340.1; AT2G38340.
DR KEGG; ath:AT2G38340; -.
DR Araport; AT2G38340; -.
DR TAIR; locus:2057217; AT2G38340.
DR eggNOG; ENOG502S30F; Eukaryota.
DR HOGENOM; CLU_1125889_0_0_1; -.
DR InParanoid; O80917; -.
DR OMA; IREPVSH; -.
DR OrthoDB; 1379296at2759; -.
DR PhylomeDB; O80917; -.
DR PRO; PR:O80917; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80917; baseline and differential.
DR Genevisible; O80917; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0034605; P:cellular response to heat; IEP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IEP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Abscisic acid signaling pathway; Activator; DNA-binding; Nucleus;
KW Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..244
FT /note="Dehydration-responsive element-binding protein 2E"
FT /id="PRO_0000112538"
FT DNA_BIND 69..134
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 20..46
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
SQ SEQUENCE 244 AA; 27370 MW; B5029169499C138F CRC64;
MEKEDNGSKQ SSSASVVSSR RRRRVVEPVE ATLQRWEEEG LARARRVQAK GSKKGCMRGK
GGPENPVCRF RGVRQRVWGK WVAEIREPVS HRGANSSRSK RLWLGTFATA AEAALAYDRA
ASVMYGPYAR LNFPEDLGGG RKKDEEAESS GGYWLETNKA GNGVIETEGG KDYVVYNEDA
IELGHDKTQN PMTDNEIVNP AVKSEEGYSY DRFKLDNGLL YNEPQSSSYH QGGGFDSYFE
YFRF
