DRE2H_ARATH
ID DRE2H_ARATH Reviewed; 157 AA.
AC Q9SIZ0; Q6J9N4;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 3.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Putative dehydration-responsive element-binding protein 2H;
DE Short=Protein DREB2H;
GN Name=DREB2H; Synonyms=ERF047; OrderedLocusNames=At2g40350;
GN ORFNames=T3G21.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY, AND FUNCTION.
RX PubMed=11798174; DOI=10.1006/bbrc.2001.6299;
RA Sakuma Y., Liu Q., Dubouzet J.G., Abe H., Shinozaki K.,
RA Yamaguchi-Shinozaki K.;
RT "DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs,
RT transcription factors involved in dehydration- and cold-inducible gene
RT expression.";
RL Biochem. Biophys. Res. Commun. 290:998-1009(2002).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Putative transcriptional activator that binds specifically to
CC the DNA sequence 5'-[AG]CCGAC-3'. {ECO:0000250,
CC ECO:0000269|PubMed:11798174}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD25670.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY560891; AAT44958.1; -; mRNA.
DR EMBL; AC007020; AAD25670.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09817.1; -; Genomic_DNA.
DR PIR; D84828; D84828.
DR RefSeq; NP_181566.2; NM_129595.3.
DR AlphaFoldDB; Q9SIZ0; -.
DR SMR; Q9SIZ0; -.
DR BioGRID; 3966; 5.
DR IntAct; Q9SIZ0; 4.
DR STRING; 3702.AT2G40350.1; -.
DR PaxDb; Q9SIZ0; -.
DR PRIDE; Q9SIZ0; -.
DR EnsemblPlants; AT2G40350.1; AT2G40350.1; AT2G40350.
DR GeneID; 818628; -.
DR Gramene; AT2G40350.1; AT2G40350.1; AT2G40350.
DR KEGG; ath:AT2G40350; -.
DR Araport; AT2G40350; -.
DR TAIR; locus:2063088; AT2G40350.
DR eggNOG; ENOG502QTBU; Eukaryota.
DR HOGENOM; CLU_1680330_0_0_1; -.
DR InParanoid; Q9SIZ0; -.
DR PhylomeDB; Q9SIZ0; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIZ0; baseline and differential.
DR Genevisible; Q9SIZ0; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0010286; P:heat acclimation; IEP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 5: Uncertain;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..157
FT /note="Putative dehydration-responsive element-binding
FT protein 2H"
FT /id="PRO_0000112541"
FT DNA_BIND 66..123
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 29..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 5..21
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT CONFLICT 96
FT /note="F -> I (in Ref. 1; AAT44958)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 157 AA; 17792 MW; 97C467BD39BB2905 CRC64;
MPRKRKSRGT RDVAEILRKW REYNEQTEAD SCIDGGGSKP IRKAPPKRSR KGCMKGKGGP
ENGICDYTGV RQRTWGKWVA EIREPGRGAK LWLGTFSSSY EAALAYDEAS KAIYGQSARL
NLPLLPLCQA RLLHFLMNLK FVHVRIQMQD LVLVRSD
