DRI_CIOIN
ID DRI_CIOIN Reviewed; 571 AA.
AC Q4H3P5;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Protein dead ringer homolog;
GN Name=Ci-DRIL1/2;
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=15269171; DOI=10.1242/dev.01270;
RA Imai K.S., Hino K., Yagi K., Satoh N., Satou Y.;
RT "Gene expression profiles of transcription factors and signaling molecules
RT in the ascidian embryo: towards a comprehensive understanding of gene
RT networks.";
RL Development 131:4047-4058(2004).
CC -!- FUNCTION: Transcription factor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355}.
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DR EMBL; AB210377; BAE06382.1; -; mRNA.
DR RefSeq; NP_001071682.1; NM_001078214.2.
DR AlphaFoldDB; Q4H3P5; -.
DR SMR; Q4H3P5; -.
DR STRING; 7719.NP_001071682.1; -.
DR Ensembl; ENSCINT00000037143; ENSCINP00000036568; ENSCING00000020478.
DR GeneID; 778579; -.
DR KEGG; cin:778579; -.
DR CTD; 778579; -.
DR eggNOG; KOG2744; Eukaryota.
DR GeneTree; ENSGT00940000169348; -.
DR HOGENOM; CLU_026952_2_1_1; -.
DR InParanoid; Q4H3P5; -.
DR OMA; FECEREK; -.
DR TreeFam; TF320364; -.
DR Proteomes; UP000008144; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.150.60; -; 1.
DR InterPro; IPR045147; ARI3A/B/C.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR023334; REKLES_domain.
DR PANTHER; PTHR15348; PTHR15348; 1.
DR Pfam; PF01388; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; SSF46774; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51486; REKLES; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..571
FT /note="Protein dead ringer homolog"
FT /id="PRO_0000295164"
FT DOMAIN 249..341
FT /note="ARID"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00355"
FT DOMAIN 473..558
FT /note="REKLES"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00819"
FT REGION 45..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 63854 MW; 56E654247FE7E014 CRC64;
MMLSNISQTK AELLSGLGSS LTSSPGNVSA ATMKLEAVME NLQRQHQQRM MEQHKNDDVI
SNDVRCDDFS DGGERQRSYS GSPKEDSDED RNDMTSPMMR DDDDVMQSDG RSPEPDKTSL
ITQQMAFAAA LAQRSSPDGS LSSLVPQAMM QHFGQFPASF DASQLPQGFR ELAMLQHQHV
AQRMAMEAQK RMQQDHNIQQ STNHIPTPSS ASSHTSSGSV TSQTNSCNGS QQEWTYEEQF
KQLYEIDDDI KRKEFLDDLF SFMQKRGTPV NRIPIMAKQV LDLYQLYRLV VEKGGLVEVI
NKKIWREITK GLNLPSSITS AAFTLRTQYM KYLYPFECER EKLSVPSELQ AAIEGNRREG
RRPSYSSHMF SYSPNTSANM LTPPKFPFAH HNGLAQLSQM AAAKYGQPDE RCLPTSPTQQ
LIAQQQQLLQ SANAQHVAAM AALETIQNQA KARQAAQQAA HHAAQQAAQH QMSLKKEIDS
DYSEGEPPEK KLSFDDSVRR LTPDNQRRSS TSSLKISMGD RGRHNEMSDV TNADSINICV
EVNGITYQGV LFAHSPNHPP VKHVTLDHPT S
