ID   DRL22_ARATH             Reviewed;         375 AA.
AC   Q9LW09;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Putative disease resistance protein At3g15700;
GN   OrderedLocusNames=At3g15700; ORFNames=MSJ11.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Potential disease resistance protein. {ECO:0000250}.
CC   -!- CAUTION: Although strongly related to the NB-LRR family, it is shorter
CC       and lacks the LRR repeats that are present in other proteins of the
CC       family. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=NIB-LRRS; Note=Functional and comparative genomics
CC       of disease resistance gene homologs;
CC       URL="http://niblrrs.ucdavis.edu";
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB017071; BAB02301.1; -; Genomic_DNA.
DR   EMBL; CP002686; ANM65825.1; -; Genomic_DNA.
DR   RefSeq; NP_188191.1; NM_112440.2.
DR   AlphaFoldDB; Q9LW09; -.
DR   SMR; Q9LW09; -.
DR   STRING; 3702.AT3G15700.1; -.
DR   PaxDb; Q9LW09; -.
DR   PRIDE; Q9LW09; -.
DR   EnsemblPlants; AT3G15700.2; AT3G15700.2; AT3G15700.
DR   GeneID; 820813; -.
DR   Gramene; AT3G15700.2; AT3G15700.2; AT3G15700.
DR   KEGG; ath:AT3G15700; -.
DR   Araport; AT3G15700; -.
DR   TAIR; locus:2093192; AT3G15700.
DR   eggNOG; KOG4658; Eukaryota.
DR   HOGENOM; CLU_000427_1_2_1; -.
DR   InParanoid; Q9LW09; -.
DR   PhylomeDB; Q9LW09; -.
DR   PRO; PR:Q9LW09; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LW09; baseline and differential.
DR   GO; GO:0005829; C:cytosol; HDA:TAIR.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.8.430; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23155; PTHR23155; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Nucleotide-binding; Plant defense;
KW   Reference proteome.
FT   CHAIN           1..375
FT                   /note="Putative disease resistance protein At3g15700"
FT                   /id="PRO_0000212754"
FT   DOMAIN          158..372
FT                   /note="NB-ARC"
FT   COILED          17..49
FT                   /evidence="ECO:0000255"
FT   BINDING         167..174
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   375 AA;  42352 MW;  639CC26119DDA146 CRC64;
     MGKDFKSMVT RCIYVGKEND NVKKLKTATE ELKDLRNIVM KRVKMYEDQQ KLKRLEKVQV
     WLRQADVAIK EAEEMLITLM SSSSSNGSSM MSFHKLDKKL CKKLKEVQEI KSRGTFDVVV
     ENSGIGSGSM MISNVDRDDQ TVGLEAVSGL VWRCMTVDNT GIIGLYGVEG VGKTTVLTQV
     NNRLLQHKLN GFDFVIWVFV SKNVNLEKIQ DTIREKIGFL DRSWMSKTEE EKAGKIFEIL
     SKRRFALFLD DVWEKVDLVK AGVPPPDGLN RSKIVFTTCS DEVCQEMGAQ TKIKMEKLPW
     ERAWDLFKMN AGEEIVKSHP DITKVAQEVA AKCDGLPLAL VTIGRAMASK KTPQEWRDAL
     YILSTSPPNF SGPIL