位置:首页 > 蛋白库 > DRL28_ARATH
DRL28_ARATH
ID   DRL28_ARATH             Reviewed;         919 AA.
AC   O81825; Q1PE46;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Probable disease resistance protein At4g27220;
GN   OrderedLocusNames=At4g27220; ORFNames=M4I22.30;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
CC   -!- FUNCTION: Probable disease resistance protein. {ECO:0000250}.
CC   -!- DOMAIN: The LRR repeats probably act as specificity determinant of
CC       pathogen recognition. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=NIB-LRRS; Note=Functional and comparative genomics
CC       of disease resistance gene homologs;
CC       URL="http://niblrrs.ucdavis.edu";
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL030978; CAA19716.1; -; Genomic_DNA.
DR   EMBL; AL161566; CAB79577.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE85312.1; -; Genomic_DNA.
DR   EMBL; DQ446872; ABE66093.1; -; mRNA.
DR   PIR; T05746; T05746.
DR   RefSeq; NP_194452.1; NM_118856.1.
DR   AlphaFoldDB; O81825; -.
DR   SMR; O81825; -.
DR   STRING; 3702.AT4G27220.1; -.
DR   PaxDb; O81825; -.
DR   PRIDE; O81825; -.
DR   EnsemblPlants; AT4G27220.1; AT4G27220.1; AT4G27220.
DR   GeneID; 828830; -.
DR   Gramene; AT4G27220.1; AT4G27220.1; AT4G27220.
DR   KEGG; ath:AT4G27220; -.
DR   Araport; AT4G27220; -.
DR   TAIR; locus:2131689; AT4G27220.
DR   eggNOG; KOG4658; Eukaryota.
DR   HOGENOM; CLU_000427_2_0_1; -.
DR   InParanoid; O81825; -.
DR   OMA; AIWIMSP; -.
DR   PhylomeDB; O81825; -.
DR   PRO; PR:O81825; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; O81825; baseline and differential.
DR   Genevisible; O81825; AT.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.8.430; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; PTHR23155; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   SMART; SM00369; LRR_TYP; 4.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Coiled coil; Leucine-rich repeat; Nucleotide-binding;
KW   Plant defense; Reference proteome; Repeat.
FT   CHAIN           1..919
FT                   /note="Probable disease resistance protein At4g27220"
FT                   /id="PRO_0000212760"
FT   DOMAIN          121..399
FT                   /note="NB-ARC"
FT   REPEAT          447..468
FT                   /note="LRR 1"
FT   REPEAT          469..492
FT                   /note="LRR 2"
FT   REPEAT          494..516
FT                   /note="LRR 3"
FT   REPEAT          519..540
FT                   /note="LRR 4"
FT   REPEAT          542..564
FT                   /note="LRR 5"
FT   REPEAT          565..587
FT                   /note="LRR 6"
FT   REPEAT          588..610
FT                   /note="LRR 7"
FT   REPEAT          611..635
FT                   /note="LRR 8"
FT   COILED          1..30
FT                   /evidence="ECO:0000255"
FT   COILED          74..95
FT                   /evidence="ECO:0000255"
FT   BINDING         141..148
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   919 AA;  103914 MW;  3C844D04ADC00CD3 CRC64;
     MFRSNARALN RALERLKNVQ TKVNEALKRS GIQEKSLERK LRIWLRKVEE NVPLGELILE
     KRSSCAIWLS DKDVEILEKV KRLEEQGQDL IKKISVNKSS REIVERVLGP SFHPQKTALE
     MLDKLKDCLK KKNVQKIGVW GMGGVGKTTL VRTLNNDLLK YAATQQFALV IWVTVSKDFD
     LKRVQMDIAK RLGKRFTREQ MNQLGLTICE RLIDLKNFLL ILDDVWHPID LDQLGIPLAL
     ERSKDSKVVL TSRRLEVCQQ MMTNENIKVA CLQEKEAWEL FCHNVGEVAN SDNVKPIAKD
     VSHECCGLPL AIITIGRTLR GKPQVEVWKH TLNLLKRSAP SIDTEEKIFG TLKLSYDFLQ
     DNMKSCFLFC ALFPEDYSIK VSELIMYWVA EGLLDGQHHY EDMMNEGVTL VERLKDSCLL
     EDGDSCDTVK MHDVVRDFAI WFMSSQGEGF HSLVMAGRGL IEFPQDKFVS SVQRVSLMAN
     KLERLPNNVI EGVETLVLLL QGNSHVKEVP NGFLQAFPNL RILDLSGVRI RTLPDSFSNL
     HSLRSLVLRN CKKLRNLPSL ESLVKLQFLD LHESAIRELP RGLEALSSLR YICVSNTYQL
     QSIPAGTILQ LSSLEVLDMA GSAYSWGIKG EEREGQATLD EVTCLPHLQF LAIKLLDVLS
     FSYEFDSLTK RLTKFQFLFS PIRSVSPPGT GEGCLAISDV NVSNASIGWL LQHVTSLDLN
     YCEGLNGMFE NLVTKSKSSF VAMKALSIHY FPSLSLASGC ESQLDLFPNL EELSLDNVNL
     ESIGELNGFL GMRLQKLKLL QVSGCRQLKR LFSDQILAGT LPNLQEIKVV SCLRLEELFN
     FSSVPVDFCA ESLLPKLTVI KLKYLPQLRS LCNDRVVLES LEHLEVESCE SLKNLPFVPG
     NTGMINEQMA WEYMSRTLG
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024