DRL32_ARATH
ID DRL32_ARATH Reviewed; 848 AA.
AC Q9FG91; Q0WKV2;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Probable disease resistance protein At5g43730;
GN OrderedLocusNames=At5g43730; ORFNames=MQD19.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable disease resistance protein. {ECO:0000250}.
CC -!- DOMAIN: The LRR repeats probably act as specificity determinant of
CC pathogen recognition. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=NIB-LRRS; Note=Functional and comparative genomics
CC of disease resistance gene homologs;
CC URL="http://niblrrs.ucdavis.edu";
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB026651; BAB11300.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95001.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69330.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69331.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69332.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69333.1; -; Genomic_DNA.
DR EMBL; AK230460; BAF02255.1; -; mRNA.
DR RefSeq; NP_001318737.1; NM_001344501.1.
DR RefSeq; NP_001331020.1; NM_001344502.1.
DR RefSeq; NP_001331021.1; NM_001344504.1.
DR RefSeq; NP_001331022.1; NM_001344503.1.
DR RefSeq; NP_199186.1; NM_123739.3.
DR AlphaFoldDB; Q9FG91; -.
DR SMR; Q9FG91; -.
DR STRING; 3702.AT5G43730.1; -.
DR PaxDb; Q9FG91; -.
DR PRIDE; Q9FG91; -.
DR ProteomicsDB; 224330; -.
DR EnsemblPlants; AT5G43730.1; AT5G43730.1; AT5G43730.
DR EnsemblPlants; AT5G43730.2; AT5G43730.2; AT5G43730.
DR EnsemblPlants; AT5G43730.3; AT5G43730.3; AT5G43730.
DR EnsemblPlants; AT5G43730.4; AT5G43730.4; AT5G43730.
DR EnsemblPlants; AT5G43730.5; AT5G43730.5; AT5G43730.
DR GeneID; 834393; -.
DR Gramene; AT5G43730.1; AT5G43730.1; AT5G43730.
DR Gramene; AT5G43730.2; AT5G43730.2; AT5G43730.
DR Gramene; AT5G43730.3; AT5G43730.3; AT5G43730.
DR Gramene; AT5G43730.4; AT5G43730.4; AT5G43730.
DR Gramene; AT5G43730.5; AT5G43730.5; AT5G43730.
DR KEGG; ath:AT5G43730; -.
DR Araport; AT5G43730; -.
DR TAIR; locus:2170892; AT5G43730.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000427_4_0_1; -.
DR InParanoid; Q9FG91; -.
DR OMA; NDIARTC; -.
DR OrthoDB; 169620at2759; -.
DR PhylomeDB; Q9FG91; -.
DR PRO; PR:Q9FG91; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FG91; baseline and differential.
DR Genevisible; Q9FG91; AT.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 1.10.8.430; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; PTHR23155; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Leucine-rich repeat; Nucleotide-binding;
KW Plant defense; Reference proteome; Repeat.
FT CHAIN 1..848
FT /note="Probable disease resistance protein At5g43730"
FT /id="PRO_0000212764"
FT DOMAIN 137..439
FT /note="NB-ARC"
FT REPEAT 534..555
FT /note="LRR 1"
FT REPEAT 558..580
FT /note="LRR 2"
FT REPEAT 582..604
FT /note="LRR 3"
FT REPEAT 605..627
FT /note="LRR 4"
FT REPEAT 629..649
FT /note="LRR 5"
FT COILED 25..62
FT /evidence="ECO:0000255"
FT BINDING 179..186
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 848 AA; 96266 MW; 700B92F16C0CB6FC CRC64;
MVDWLSLLPW NKIFTAACGC FLSDSNYIHL MESNLDALQK TMEELKNGRD DLLARVSIEE
DKGLQRLALV NGWLSRVQIV ESEFKDLLEA MSIETGRLCL FGYCSEDCIS SYNYGGKVMK
NLEEVKELLS KKNFEVVAQK IIPKAEKKHI QTTVGLDTMV GIAWESLIDD EIRTLGLYGM
GGIGKTTLLE SLNNKFVELE SEFDVVIWVV VSKDFQLEGI QDQILGRLRP DKEWERETES
KKASLINNNL KRKKFVLLLD DLWSEVDLIK IGVPPPSREN GSKIVFTTRS KEVCKHMKAD
KQIKVDCLSP DEAWELFRLT VGDIILRSHQ DIPALARIVA AKCHGLPLAL NVIGKAMVCK
ETVQEWRHAI NVLNSPGHKF PGMEERILPI LKFSYDSLKN GEIKLCFLYC SLFPEDFEIE
KDKLIEYWIC EGYINPNRYE DGGTNQGYDI IGLLVRAHLL IECELTDKVK MHDVIREMAL
WINSDFGNQQ ETICVKSGAH VRLIPNDISW EIVRQMSLIS TQVEKIACSP NCPNLSTLLL
PYNKLVDISV GFFLFMPKLV VLDLSTNWSL IELPEEISNL GSLQYLNLSL TGIKSLPVGL
KKLRKLIYLN LEFTNVLESL VGIATTLPNL QVLKLFYSLF CVDDIIMEEL QRLKHLKILT
ATIEDAMILE RVQGVDRLAS SIRGLCLRNM SAPRVILNSV ALGGLQQLGI VSCNISEIEI
DWLSKERRDH RSTSSPGFKQ LASITVIGLV GPRDLSWLLF AQNLKDIQVQ YSPTIEEIIN
KQKGMSITKV HRDIVVPFGK LESLHLYQLA ELTEICWNYQ TLPNLRESYV NYCPKLLEDI
ANFPKLKG
