DRL37_ARATH
ID DRL37_ARATH Reviewed; 843 AA.
AC Q9LVT4; Q0WVJ2;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Probable disease resistance protein At5g47250;
GN OrderedLocusNames=At5g47250; ORFNames=MQL5.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable disease resistance protein. {ECO:0000250}.
CC -!- DOMAIN: The LRR repeats probably act as specificity determinant of
CC pathogen recognition. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=NIB-LRRS; Note=Functional and comparative genomics
CC of disease resistance gene homologs;
CC URL="http://niblrrs.ucdavis.edu";
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DR EMBL; AB018117; BAA97159.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95491.1; -; Genomic_DNA.
DR EMBL; AK226756; BAE98856.1; -; mRNA.
DR RefSeq; NP_199536.1; NM_124096.4.
DR AlphaFoldDB; Q9LVT4; -.
DR SMR; Q9LVT4; -.
DR STRING; 3702.AT5G47250.1; -.
DR iPTMnet; Q9LVT4; -.
DR PaxDb; Q9LVT4; -.
DR PRIDE; Q9LVT4; -.
DR ProteomicsDB; 224335; -.
DR EnsemblPlants; AT5G47250.1; AT5G47250.1; AT5G47250.
DR GeneID; 834772; -.
DR Gramene; AT5G47250.1; AT5G47250.1; AT5G47250.
DR KEGG; ath:AT5G47250; -.
DR Araport; AT5G47250; -.
DR TAIR; locus:2171579; AT5G47250.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000427_4_0_1; -.
DR InParanoid; Q9LVT4; -.
DR OMA; WLMYAAN; -.
DR OrthoDB; 236715at2759; -.
DR PhylomeDB; Q9LVT4; -.
DR PRO; PR:Q9LVT4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LVT4; baseline and differential.
DR Genevisible; Q9LVT4; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23155; PTHR23155; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS51450; LRR; 5.
PE 2: Evidence at transcript level;
KW ATP-binding; Coiled coil; Leucine-rich repeat; Nucleotide-binding;
KW Plant defense; Reference proteome; Repeat.
FT CHAIN 1..843
FT /note="Probable disease resistance protein At5g47250"
FT /id="PRO_0000212769"
FT DOMAIN 141..440
FT /note="NB-ARC"
FT REPEAT 510..531
FT /note="LRR 1"
FT REPEAT 535..556
FT /note="LRR 2"
FT REPEAT 559..581
FT /note="LRR 3"
FT REPEAT 583..604
FT /note="LRR 4"
FT REPEAT 606..628
FT /note="LRR 5"
FT COILED 28..58
FT /evidence="ECO:0000255"
FT BINDING 183..190
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 843 AA; 94801 MW; EE67031445D822CF CRC64;
MNCCWQVVEP CYKSALSYLC VKVGNICMLK ENLVLLKSAF DELKAEKEDV VNRVNAGELK
GGQRLAIVAT WLSQVEIIEE NTKQLMDVAS ARDASSQNAS AVRRRLSTSG CWFSTCNLGE
KVFKKLTEVK SLSGKDFQEV TEQPPPPVVE VRLCQQTVGL DTTLEKTWES LRKDENRMLG
IFGMGGVGKT TLLTLINNKF VEVSDDYDVV IWVESSKDAD VGKIQDAIGE RLHICDNNWS
TYSRGKKASE ISRVLRDMKP RFVLLLDDLW EDVSLTAIGI PVLGKKYKVV FTTRSKDVCS
VMRANEDIEV QCLSENDAWD LFDMKVHCDG LNEISDIAKK IVAKCCGLPL ALEVIRKTMA
SKSTVIQWRR ALDTLESYRS EMKGTEKGIF QVLKLSYDYL KTKNAKCFLY CALFPKAYYI
KQDELVEYWI GEGFIDEKDG RERAKDRGYE IIDNLVGAGL LLESNKKVYM HDMIRDMALW
IVSEFRDGER YVVKTDAGLS QLPDVTDWTT VTKMSLFNNE IKNIPDDPEF PDQTNLVTLF
LQNNRLVDIV GKFFLVMSTL VVLDLSWNFQ ITELPKGISA LVSLRLLNLS GTSIKHLPEG
LGVLSKLIHL NLESTSNLRS VGLISELQKL QVLRFYGSAA ALDCCLLKIL EQLKGLQLLT
VTVNNDSVLE EFLGSTRLAG MTQGIYLEGL KVSFAAIGTL SSLHKLEMVN CDITESGTEW
EGKRRDQYSP STSSSEITPS NPWFKDLSAV VINSCIHLKD LTWLMYAANL ESLSVESSPK
MTELINKEKA QGVGVDPFQE LQVLRLHYLK ELGSIYGSQV SFPKLKLNKV DIENCPNLHQ
RPL
