DRL38_ARATH
ID DRL38_ARATH Reviewed; 948 AA.
AC Q9LVT3;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 2.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Probable disease resistance protein At5g47260;
GN OrderedLocusNames=At5g47260; ORFNames=MQL5.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Potential disease resistance protein. {ECO:0000250}.
CC -!- DOMAIN: The LRR repeats probably act as specificity determinant of
CC pathogen recognition. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA97160.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC -!- WEB RESOURCE: Name=NIB-LRRS; Note=Functional and comparative genomics
CC of disease resistance gene homologs;
CC URL="http://niblrrs.ucdavis.edu";
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DR EMBL; AB018117; BAA97160.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95492.1; -; Genomic_DNA.
DR RefSeq; NP_199537.2; NM_124097.2.
DR AlphaFoldDB; Q9LVT3; -.
DR SMR; Q9LVT3; -.
DR STRING; 3702.AT5G47260.1; -.
DR PaxDb; Q9LVT3; -.
DR PRIDE; Q9LVT3; -.
DR ProteomicsDB; 224336; -.
DR EnsemblPlants; AT5G47260.1; AT5G47260.1; AT5G47260.
DR GeneID; 834773; -.
DR Gramene; AT5G47260.1; AT5G47260.1; AT5G47260.
DR KEGG; ath:AT5G47260; -.
DR Araport; AT5G47260; -.
DR TAIR; locus:2171589; AT5G47260.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000427_4_0_1; -.
DR InParanoid; Q9LVT3; -.
DR OMA; VEEWISM; -.
DR OrthoDB; 236715at2759; -.
DR PhylomeDB; Q9LVT3; -.
DR PRO; PR:Q9LVT3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LVT3; baseline and differential.
DR Genevisible; Q9LVT3; AT.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 1.10.8.430; -; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; PTHR23155; 1.
DR Pfam; PF04548; AIG1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Leucine-rich repeat; Nucleotide-binding;
KW Plant defense; Reference proteome; Repeat.
FT CHAIN 1..948
FT /note="Probable disease resistance protein At5g47260"
FT /id="PRO_0000212770"
FT DOMAIN 134..432
FT /note="NB-ARC"
FT REPEAT 498..519
FT /note="LRR 1"
FT REPEAT 520..542
FT /note="LRR 2"
FT REPEAT 545..567
FT /note="LRR 3"
FT REPEAT 569..591
FT /note="LRR 4"
FT REPEAT 592..614
FT /note="LRR 5"
FT REPEAT 615..636
FT /note="LRR 6"
FT REPEAT 640..661
FT /note="LRR 7"
FT REPEAT 666..686
FT /note="LRR 8"
FT REPEAT 690..711
FT /note="LRR 9"
FT COILED 20..57
FT /evidence="ECO:0000255"
FT BINDING 176..183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 948 AA; 107732 MW; F68165E10196F395 CRC64;
MGNNFSVESP SLAPFLCGKR KYLYNLERNL EALHKVMQDL NAMRNDLLKR LSKEEEIGLQ
GLQEVKEWIS MVEEIEPKAN RLLDESVSEI QRLSRYGYCS LIPASTYRYS EKVLTTMEGV
ETLRSKGVFE AVVHRALPPL VIKMPPIQLT VSQAKLLDTA WARLMDINVG TLGIYGRGGV
GKTTLLTKLR NKLLVDAFGL VIFVVVGFEE VESIQDEIGK RLGLQWRRET KERKAAEILA
VLKEKRFVLL LDGIQRELDL EEIGVPFPSR DNGCKIVFTT QSLEACDESK WVDAKVEITC
LSPEEAWDLF QETVGENTLR SHQDIPKLAR VVASTCRGLP LALNLIGEAM SGKRTVREWR
YTIHVLASST AEFPDMEDGT LPILKSIYDN MSDEIIRLCF LYCALFPENL DIGKEDLVNY
WICEGILAKE DREEAEIQGY EIICDLVRMR LLMESGNGNC VKMHGMVREM ALWIASEHFV
VVGGERIHQM LNVNDWRMIR RMSVTSTQIQ NISDSPQCSE LTTLVFRRNR HLKWISGAFF
QWMTGLVVLD LSFNRELAEL PEEVSSLVLL RFLNLSWTCI KGLPLGLKEL KSLIHLDLDY
TSNLQEVDVI ASLLNLQVLR LFHSVSMDLK LMEDIQLLKS LKELSLTVRG SSVLQRLLSI
QRLASSIRRL HLTETTIVDG GILSLNAIFS LCELDILGCN ILEITIDWRC TIQREIIPQF
QNIRTMTIHR CEYLRDLTWL LLAPCLGELS VSECPQMEEV ISKDKAMAKL GNTSEQPFQN
LTKLVLDGLP KLESIYWTPL PFPVLEYLVI RRCPELRRLP FNSESTIGNQ VETIIEEQVI
KIVEWEDEAT KQRFSHFNNR DFVQMAEDPK MDGLTSESHP IQTIDLVGTT GSGETATANN
IQGKKVVQSG THATVVTMEC QTYKVFTPDC PINNMIDTPG TNFLLCYT
