ID   DRNG_AERHY              Reviewed;         227 AA.
AC   O31222;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2002, sequence version 2.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Extracellular deoxyribonuclease;
DE            Short=DNase;
DE            EC=3.1.21.-;
DE   Flags: Precursor;
OS   Aeromonas hydrophila.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=644;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14715 / LMG 13663;
RA   Joh K., Myung H., Nam I.Y.;
RT   "Purification and characterization of an extracellular nuclease from
RT   Aeromonas hydrophila ATCC 14715.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EndA/NucM nuclease family. {ECO:0000305}.
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DR   EMBL; AF004392; AAB61738.2; -; Genomic_DNA.
DR   AlphaFoldDB; O31222; -.
DR   SMR; O31222; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   InterPro; IPR007346; Endonuclease-I.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   PANTHER; PTHR33607; PTHR33607; 1.
DR   Pfam; PF04231; Endonuclease_1; 1.
DR   SUPFAM; SSF54060; SSF54060; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..227
FT                   /note="Extracellular deoxyribonuclease"
FT                   /id="PRO_0000007832"
SQ   SEQUENCE   227 AA;  26509 MW;  487884EAF63A1BA8 CRC64;
     MFRPLLSFTL ARLVSLPLHA QTFRAAKQDL NRLYQDHPVT FYCGCKIEYQ GKKMSPDLAS
     CGYEPRKQAK RANRIEWEHV VPAWEFGHQL QCWQQGGRKN CGKTDEFNQM EGDMHNLFPA
     IGEVNVDRAN YRFSDWNGTP HQYGQCQMLV DFKERQVQPP KGLVRGQIAR AYLYMSQQYG
     PGLAAQQRKL FEAWDRQYPA DGWECERNRR IGKLQGNTNP FIEKQCQ