ID   DSA2B_TORMA             Reviewed;         107 AA.
AC   Q91499;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Dispanin subfamily A member 2b;
DE            Short=DSPA2b;
DE   AltName: Full=14 kDa transmembrane protein;
OS   Torpedo marmorata (Marbled electric ray).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Batoidea; Torpediniformes; Torpedinidae; Torpedo.
OX   NCBI_TaxID=7788;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Liver;
RA   Meunier F.-M., Birman S., O'Regan S., Leroy C., Morel N., Brochier G.,
RA   Varoqui H., Lesbats B., Le Caer J.-P., Rossier J., Israel M.;
RL   Submitted (NOV-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   TISSUE SPECIFICITY.
RX   PubMed=2055963; DOI=10.1242/jcs.98.3.351;
RA   Morel N., Brochier G., Synguelakis M., Le Gal La Salle G.;
RT   "Immunological identification of a new 14X10(3) Mr membrane-bound protein
RT   in Torpedo electric organ.";
RL   J. Cell Sci. 98:351-361(1991).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=22363774; DOI=10.1371/journal.pone.0031961;
RA   Sallman Almen M., Bringeland N., Fredriksson R., Schioth H.B.;
RT   "The dispanins: a novel gene family of ancient origin that contains 14
RT   human members.";
RL   PLoS ONE 7:E31961-E31961(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed various cell types in torpedo electric
CC       organ and muscle, especially fibroblasts, capillary endothelial cells,
CC       and axonal cuff cells. {ECO:0000269|PubMed:2055963}.
CC   -!- SIMILARITY: Belongs to the CD225/Dispanin family. {ECO:0000305}.
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DR   EMBL; U16697; AAC59660.1; -; mRNA.
DR   AlphaFoldDB; Q91499; -.
DR   TCDB; 8.A.58.1.5; the dispanin (dispanin) family.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007593; CD225/Dispanin_fam.
DR   Pfam; PF04505; CD225; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..107
FT                   /note="Dispanin subfamily A member 2b"
FT                   /id="PRO_0000153731"
FT   TOPO_DOM        1..31
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        53..77
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..107
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   LIPID           41
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           42
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   107 AA;  11651 MW;  DE418B0050512091 CRC64;
     MEYRTDQVPM SPRSVQGAPG TLPIRDHLPW SIFNLFYMNV CCLGLTAMIF SVKSRDRKVV
     GDVEGARHYG STARSLNIAA TVLGILLIII LIGLAATGTI QALKYKG