ID   DSBA_BPT4               Reviewed;          89 AA.
AC   P13320;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   23-FEB-2022, entry version 72.
DE   RecName: Full=Double-stranded DNA-binding protein;
DE   AltName: Full=DsDNA-binding protein A;
GN   Name=dsbA; Synonyms=rpbB;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BK536;
RX   PubMed=2674900; DOI=10.1093/nar/17.16.6729;
RA   Hahn S., Rueger W.;
RT   "Organization of the bacteriophage T4 genome between map positions 150.745
RT   and 145.824.";
RL   Nucleic Acids Res. 17:6729-6729(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   FUNCTION.
RX   PubMed=2017138; DOI=10.1007/bf00261683;
RA   Gansz A., Kruse U., Rueger W.;
RT   "Gene product dsbA of bacteriophage T4 binds to late promoters and enhances
RT   late transcription.";
RL   Mol. Gen. Genet. 225:427-433(1991).
RN   [4]
RP   SUBUNIT.
RX   PubMed=9504717; DOI=10.1515/bchm.1998.379.1.51;
RA   Sieber P., Lindemann A., Boehm M., Seidel G., Herzing U.,
RA   van der Heusen P., Muller R., Ruger W., Jaenicke R., Rosch P.;
RT   "Overexpression and structural characterization of the phage T4 protein
RT   DsbA.";
RL   Biol. Chem. 379:51-58(1998).
CC   -!- FUNCTION: May play a role in transcription of several T4 genes. Binds
CC       double-stranded DNA and interacts preferentially with T4 late promoter
CC       regions. {ECO:0000269|PubMed:2017138}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000269|PubMed:9504717}.
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DR   EMBL; X15818; CAA33813.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42567.1; -; Genomic_DNA.
DR   PIR; S05557; S05557.
DR   RefSeq; NP_049858.1; NC_000866.4.
DR   SMR; P13320; -.
DR   GeneID; 1258620; -.
DR   KEGG; vg:1258620; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR020313; Double-stranded_DNA-bd.
DR   Pfam; PF11126; Phage_DsbA; 1.
PE   1: Evidence at protein level;
KW   DNA replication; DNA-binding; Reference proteome.
FT   CHAIN           1..89
FT                   /note="Double-stranded DNA-binding protein"
FT                   /id="PRO_0000164931"
SQ   SEQUENCE   89 AA;  10379 MW;  0152649899E09319 CRC64;
     MAKKEMVEFD EAIHGEDLAK FIKEASDHKL KISGYNELIK DIRIRAKDEL GVDGKMFNRL
     LALYHKDNRD VFEAETEEVV ELYDTVFSK