ID   ADF3_MAIZE              Reviewed;         139 AA.
AC   Q41764;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Actin-depolymerizing factor 3;
DE            Short=ADF-3;
DE            Short=ZmADF3;
DE   AltName: Full=ZmABP3;
GN   Name=ADF3; Synonyms=ABP3;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND CHARACTERIZATION.
RC   TISSUE=Leaf;
RX   PubMed=8693008; DOI=10.1073/pnas.93.14.7415;
RA   Lopez I., Anthony R.G., Maciver S.K., Jiang C.J., Khan S., Weeds A.G.,
RA   Hussey P.J.;
RT   "Pollen specific expression of maize genes encoding actin depolymerizing
RT   factor-like proteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:7415-7420(1996).
RN   [2]
RP   CHARACTERIZATION.
RX   PubMed=9418045; DOI=10.1046/j.1365-313x.1997.12051035.x;
RA   Jiang C.J., Weeds A.G., Hussey P.J.;
RT   "The maize actin-depolymerizing factor, ZmADF3, redistributes to the
RT   growing tip of elongating root hairs and can be induced to translocate into
RT   the nucleus with actin.";
RL   Plant J. 12:1035-1043(1997).
CC   -!- FUNCTION: Actin-depolymerizing protein. Severs actin filaments (F-
CC       actin) and binds to actin monomers.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=As root hairs emerges and the
CC       microfilament bundles redirect to the outgrowth ADF3 concentrates at
CC       the tip of the emerging hair and remains in this position as elongation
CC       proceeds.
CC   -!- TISSUE SPECIFICITY: Expressed in all tissues except pollen.
CC   -!- SIMILARITY: Belongs to the actin-binding proteins ADF family.
CC       {ECO:0000305}.
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DR   EMBL; X97726; CAA66311.1; -; mRNA.
DR   PIR; T02914; T02914.
DR   RefSeq; NP_001105474.1; NM_001112004.1.
DR   AlphaFoldDB; Q41764; -.
DR   SMR; Q41764; -.
DR   STRING; 4577.GRMZM2G060702_P02; -.
DR   iPTMnet; Q41764; -.
DR   PaxDb; Q41764; -.
DR   EnsemblPlants; Zm00001eb062600_T001; Zm00001eb062600_P001; Zm00001eb062600.
DR   GeneID; 542445; -.
DR   Gramene; Zm00001eb062600_T001; Zm00001eb062600_P001; Zm00001eb062600.
DR   eggNOG; KOG1735; Eukaryota.
DR   OMA; HRFITYK; -.
DR   OrthoDB; 1370477at2759; -.
DR   Proteomes; UP000007305; Chromosome 1.
DR   ExpressionAtlas; Q41764; baseline and differential.
DR   Genevisible; Q41764; ZM.
DR   GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR   GO; GO:0030042; P:actin filament depolymerization; IBA:GO_Central.
DR   CDD; cd11286; ADF_cofilin_like; 1.
DR   Gene3D; 3.40.20.10; -; 1.
DR   InterPro; IPR002108; ADF-H.
DR   InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR   InterPro; IPR017904; ADF/Cofilin.
DR   PANTHER; PTHR11913; PTHR11913; 1.
DR   Pfam; PF00241; Cofilin_ADF; 1.
DR   SMART; SM00102; ADF; 1.
DR   PROSITE; PS51263; ADF_H; 1.
PE   1: Evidence at protein level;
KW   Actin-binding; Cytoplasm; Reference proteome.
FT   CHAIN           1..139
FT                   /note="Actin-depolymerizing factor 3"
FT                   /id="PRO_0000214934"
FT   DOMAIN          7..139
FT                   /note="ADF-H"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00599"
SQ   SEQUENCE   139 AA;  15900 MW;  28FC82C518022C87 CRC64;
     MANARSGVAV NDECMLKFGE LQSKRLHRFI TFKMDDKFKE IVVDQVGDRA TSYDDFTNSL
     PENDCRYAIY DFDFVTAEDV QKSRIFYILW SPSSAKVKSK MLYASSNQKF KSGLNGIQVE
     LQATDASEIS LDEIKDRAR